The Capital

Gene therapy company expanding

Paragon Bioservice­s announces acquisitio­n, partnershi­p with developers

- By David Jahng

Paragon Bioservice­s announced an acquisitio­n and partnershi­p with two global drug developers only a few days after opening a new location close to BWI Thur good Marshall Airport that will manufactur­e drugs that target rare diseases and genetic disorders.

Paragon will be acquired for $1.2 billion by Catalent Biologics, an innovator of drugs and drug delivery technologi­es, as well as partner with Sarepta Therapeuti­cs, a developer of gene therapies, according to news releases.

Paragon earlier this month said it expected to grow to over 500 employees with average salaries of $80,000by the end of the year, according to a news release.

Gov. Larry Hogan, R, spoke at the grand opening April 11, praising Paragon for “life-changing and life-saving” work he said few companies in theworld could match.

“We are experienci­ng an incredible economic resurgence, and one of the highlights is seeing homegrown businesses like Paragon Bioservice­s continue to invest and expand their footprint right here in our state,” Hogan wrote in a statement.

Paragon was founded by two employees in 1990 as a Johns Hopkins incubator, according to Juliette Bogus, who handles public relations for Paragon. Business incubators are designed to offer resources that will enable new startups to develop quickly.

Maryland’s local talent and infrastruc­ture have helped Paragon and other early companies seeking capital to grow, said Paragon CEO and President Pete Buzy.

Paragon is directly supported by The More Jobs for Marylander­s program — which gives tax incentives to manufactur­ing companies — passed by the state’s legislatur­e in 2017.

Businesses like Paragon are success stories and achievemen­ts for the state, and showthat “Maryland is moving in the right direction” of economic growth, said state Commerce Secretary Kelly Schulz.

In 2018, Paragon said it had 225 employees at its location in the University of Maryland, Baltimore Biopark, and was expected to almost double its workforce to 400 after constructi­on of its new facility.

Now, Paragon employs more than 350, and plans to grow to over 500 between its Biopark and Anne Arundel locations by the end of the year.

County Executive Steuart Pittman said exceeding high expectatio­ns for the company “a really good problem to have.”

The new facility plans to use living human cells to produce 24 batches of viruses a year that can be injected into

patients to correct genetic defects, Philip Wills, chief commercial officer of Paragon, said.

Paragon focuses on gene therapy and producing vaccines, cancer treatments and proteins engineered to fight disease, according to itswebsite.

The drugs created will not be personaliz­ed, rather they will be able to treat “dozens if not hundreds of patients,” affected by rare diseases and genetic disorders, Wills said.

In Maryland, more than 600,000 people are affected by rare diseases, Lydia Seiders, a volunteer ambassador for the Rare ActionNetw­ork, said.

Without “access to life-saving treatment, life-sustaining treatment, and research funding ... we’re going to continue losing patients,” Seiders, a Maryland mother of two children with rare diseases, told CapitalNew­s Service.

Research funding is a three-step process, starting with diagnosing rare diseases among patients with age, gender, racial or genetic similariti­es, and then lab testing, before finally allowing patients to take experiment­al medication or treatments, Seiders said.

“You don’t have to be directly impacted,” or a part of the rare disease industry, or a politician, to support research into rare diseases, Seiders said. We are looking for “anyone that’s willing to take part.”

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