The Capital

Treatment trials seek the recently exposed, positive volunteers

- By Danielle Ohl

Dr. Shmuel Shoham, a Johns Hopkins researcher, said antibody-rich plasma is a 100-year-old tool in the fight against different diseases that medicine doesn’t have antibiotic­s to treat.

Researcher­s seek Annapolis-area residents to participat­e in clinical trials that explore whether blood plasma donated by someone who previously had COVID-19 can treat those with a new case of the same infection.

The trial is recruiting participan­ts who have been recently exposed to a confirmed case of COVID-19 but are not yet showing symptoms, as well as those who have just received a positive COVID-19 diagnosis but are not hospitaliz­ed.

While state and local health officials expect COVID-19 vaccines to proliferat­e by the summer, COVID-19 is still a danger to those who haven’t been vaccinated. Doctors and medical researcher­s are still pursuing treatments for the disease, which reached Anne Arundel County a year ago this week.

One such treatment is convalesce­nt plasma, the liquid part of blood that, in patients who already caught and overcame COVID-19, contains antibodies that could fend off the disease in others.

Dr. Shmuel Shoham, a Johns Hopkins researcher, said antibody-rich plasma is a 100-yearold tool in the fight against different diseases that medicine doesn’t have antibiotic­s to treat. Shoham and partners across the country, including at the Anne Arundel Research Center in Annapolis, have found over the last year that the convalesce­nt plasma has the potential to help people early on in their infection rather than at critical later stages, he said.

“For people who don’t respond well to vaccines, people who didn’t get the vaccine,” the pandemic is not going to be over, Shoham said, “and we still need treatments for those people.”

The ongoing studies seek volunteers who had close contact with a COVID-19-positive person within the last three days or someone who tested positive in the last five days. Half the selected volunteers will receive the plasma; the other half will receive a placebo. The study is double-blind, meaning neither the volunteers nor the researcher­s know who received treatment and who did not.

Participan­ts will be paid for their time. Those selected will be given an appointmen­t for a transfusio­n.

During the appointmen­t, participan­ts will sit for an infusion through an IV over about an hour, Shoham said. Following the treatment, participan­ts will sit for another half hour for monitoring.

To learn more or sign up for the study, go to covidplasm­atrial.org or call 888-506-1199.

As part of its series “COVID-19: One Year Later,” The Capital asked readers to share their stories and perspectiv­es. More of what you sent will appear in the Monday edition.

A long-time Annapolis resident is celebratin­g a milestone on March 1. This year, Margaret Scholz celebrated her 100th birthday.

Mrs. Scholz was born March 1, 1921 in Sir Johns Run, West Virginia to Elmer and Pearl Haddox. She was the youngest of four daughters.

She enjoyed a career after graduating from Marinello Beauty School in Baltimore and was married to her husband Walter Scholz from 1941 until his passing in 1971. They spent some time living in California before returning to the East Coast and residing in Annapolis. They had five children together.

Celebratin­g this milestone across the country along with her children are her 10 grandchild­ren, 3 great-grandchild­ren and one great-great-grandchild along with a multitude of cousins, nieces and nephews.

She has enjoyed a life of spending time with her family and traveling, as she has been very active in her retirement. Annually, the family has gathered every summer at Cacapon State Park to celebrate and reflect on the year. Due to this past year’s pandemic, this matriarch and her family did not meet for the first time in over 50 years!

 ?? CECELIA HUNTER/FOR CAPITAL GAZETTE ?? Margaret Scholz, a longtime Annapolis resident, turned 100 on March 1. This year, she celebrated with family at a distance, but previous birthdays have brought the family together.
CECELIA HUNTER/FOR CAPITAL GAZETTE Margaret Scholz, a longtime Annapolis resident, turned 100 on March 1. This year, she celebrated with family at a distance, but previous birthdays have brought the family together.

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