The Capital

Follow up on all fractures

Mounting evidence shows that a break resulting from any kind of trauma is a sign to check bone health for older men and women

- By Jane E. Brody

Let’s say you’re a woman in your mid-50s, or perhaps a man in your early 70s, and you break a leg or a hip after falling from a 6-foot ladder. That would be distressin­g, to be sure, but neither you nor your doctor would probably be surprised by the severity of your injury given the nature of the accident.

And chances are your doctor would probably not warn you after your fall that weakened bones may have contribute­d to your break, or that you might be at risk of breaking another bone next time from a minor mishap, such as tripping over the dog. And so, after the break is immobilize­d in a cast or surgically repaired, your doctor would probably do nothing more to head off the possibilit­y of a future fracture.

Physicians are trained to think that only bones that break after minimal or no trauma are a sign of fragile bones. And that such breaks are the only ones that warrant an evaluation of the patient’s bone health, as well as treatment and counseling to prevent another broken bone. Furthermor­e, profession­al recommenda­tions reinforce this thinking and prompt doctors to discharge patients after a high-trauma fracture is repaired.

Yet, there is now mounting evidence that for women past menopause and men in their Medicare years, a broken bone from any kind of trauma — whether it’s severe (car accident) or not (fall on the sidewalk) — can probably be attributed to fragile bones.

In a commentary published in JAMA Internal Medicine in June, Dr. Anne Schafer and Dr. Dolores Shoback of the San Francisco Veterans Affairs Health Care System suggested that fractures following either serious or minimal trauma represent “a distinctio­n without a difference” for middleaged and older people. No matter how the accident occurred, current evidence indicates that when an older person breaks a bone, further evaluation of that person’s overall bone health and advice on how to maintain it should follow as an integral part of treatment.

The JAMA Internal Medicine commentary was a response to a major new study published in the same issue of the journal. The study cataloged the incidence of subsequent fractures among 7,142 postmenopa­usal women, many in their 50s and 60s, who had sustained a first fracture, and compared their risk of having a second fracture to 66,874 of their peers who had not had an initial fracture. The researcher­s followed the women for an average of about eight years.

Among the women who sustained an initial fracture from minimal trauma, which is considered a hallmark of weakened bones, their risk of having another fracture increased by 52%. Among the women whose first fracture followed a traumatic accident, such as falling off a ladder, the risk of a second fracture was 25% greater than would have been expected based on women who had no initial fracture.

The study’s authors concluded from their statistica­l analysis that both “nontraumat­ic and traumatic initial fractures” were “similarly associated with risk of subsequent fracture.”

Contrary to current guidelines, the authors wrote, “our study’s results are clinically important because, in contrast to a nontraumat­ic fracture, a fracture that is considered traumatic often does not trigger further evaluation for osteoporos­is or counseling regarding increased subsequent fracture risk.” However, they added, “high-trauma and low-trauma fractures show similar associatio­ns with low bone mineral density.”

Even younger postmenopa­usal women who have sustained a serious fracture, studies have found, are at higher risk of having osteoporos­is, said Dr. Sundeep Khosla, a bone expert at the Mayo Clinic in Rochester, Minnesota.

“The evidence is pretty compelling that postmenopa­usal women who fracture, regardless of the level of trauma, should have their bone density evaluated,” he told me. “A fracture suffered in a fall from a standing height confers almost as high a risk of a second fracture as if the first fracture resulted from falling down the stairs.”

Men also face an oftenignor­ed risk of second fractures, especially because their first fractures are more likely to result from a traumatic event such as a car accident and are not recognized as a harbinger of future fractures, Schafer said. Dr. Carolyn Crandall, an internal medicine physician at UCLA’s David Geffen School of Medicine who led the JAMA Internal Medicine study, said recent studies have documented that older men who suffered a high-trauma fracture were often as likely to have low bone densities as men with a low-trauma fracture and were also at risk of a future fracture.

“Older men may be at a particular disadvanta­ge if we brush off their hightrauma fractures,” Schafer said. “Men do lose bone with age and develop osteoporos­is, though generally later in life than women. They’ve been overlooked. Men who have fractured bones in the past should not be brushed off.”

What, then, is the message for older men and middle-aged and older women and for their physicians?

For starters, the question doctors usually ask — “How did this break occur?” — is not relevant. What counts, Khosla said, is the health of the patient’s bones, and that is determined by a bone density test that measures the mineral content of bones in the spine, hips and sometimes the forearm. The test is painless, noninvasiv­e and brief, and its results are best interprete­d by a specialist in osteoporos­is.

If the test shows abnormally weakened bones, doctors usually prescribe medication to slow, stop or reverse the process. Treatment should also include lifestyle counseling on diet and exercise, Khosla said.

“Being physically active helps to maintain strength, balance and agility and decreases the chances of falling and breaking a bone.” Weight-bearing and strength-building exercises are important throughout life.

 ?? GRACIA LAM/THE NEW YORK TIMES ??
GRACIA LAM/THE NEW YORK TIMES

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