The Commercial Appeal

New rules urge earlier treatment of AIDS virus

- By Maria Cheng

LONDON — Young children and certain other people with the AIDS virus should be started on medicines as soon as they are diagnosed, the World Health Organizati­on says in new guidelines that also recommend earlier treatment for adults.

The advice will have the most impact in Africa, where nearly 70 percent of people with HIV live. Many rich countries already advocate early treatment. WHO’s new guidelines were released Sunday at the Internatio­nal AIDS Society meeting in Kuala Lumpur, Malaysia.

About 34 million people worldwide have HIV, the virus that causes AIDS. HIV attacks key infection-fighting cells of the immune system known as T-cells. When that count drops to 200, people are considered to have AIDS. In the past, WHO recommende­d countries start treating people with HIV when their T-cell count fell to 350; a normal count is between 500 and 1,600.

The new recommenda­tions say to treat earlier, when the T-cell count hits 500.

In addition to children under 5, WHO says several other groups should also get AIDS drugs as soon as they’re diagnosed with HIV: pregnant and breastfeed­ing women, people whose partners are uninfected and those who have tuberculos­is or hepatitis B.

The new guidelines mean an additional 9 million people in developing countries will now be eligible for treatment. At the moment, only about 60 percent of people who need the life-saving drugs are getting them.

“WHO has recognized that time is the most im- portant commodity when it comes to battling the HIV epidemic,” said Sharonann Lynch, HIV policy adviser at Doctors Without Borders, which contribute­d to the new guidelines.

She said that while the costs for rolling out this treatment might be expensive, the strategy would ultimately result in fewer HIV infections and deaths in the future.

“It’s pay now or pay later,” she said.

The new guidelines also mean the total global spending on AIDS — about $23 billion a year — will rise by about 10 percent, according to Gottfried Hirnschall, director of WHO’s HIV department. Given the ongoing financial crisis, it’s unclear how willing donors will be to pitch in for even more AIDS treatments.

Hirnschall said the cheapest course of the drugs costs $127 per person every year under programs that have negotiated prices for poor countries, but the price can be much higher elsewhere. WHO’s recommende­d t reatment is a single pill that combines three powerful drugs taken once daily.

WHO’s new guidelines are based largely on recent studies suggesting people with HIV who start treatment before their immune systems weaken live longer.

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