The Commercial Appeal

Human fetal tissue long used for variety of medical studies

- By Malcolm Ritter

Associated Press

Controvers­y over Planned Parenthood’s supplying fetal tissue for research has focused attention on a little-discussed aspect of science.

Some of the organizati­on’s affiliates, in fewer than five states, provide the tissue, according to Planned Parenthood. An anti-abortion group says the group is illegally making a profit from that, and has released covertly recorded videos about it.

Planned Parenthood says it receives only reimbursem­ents for costs of providing tissue donated by women, and that it has done nothing illegal or improper.

Some basic facts about fetal tissue in research:

Q: What is fetal tissue used for?

A: Tissue from elective abortions and miscarriag­es is used for a wide variety of purposes. Scientists who want to regenerate In a new

pilot program, California

utility Pacific Gas & Electric is paying drivers of BMW

electric cars to delay charging their vehicles when the power grid

is under pressure. organs and tissues may use it to learn how the human body makes them in the first place. Others look for defects in early developmen­t that can cause disease or miscarriag­e, or study normal developmen­t, which can guide therapeuti­c strategies. The tissue is also used to learn how medicines or toxins affect a fetus.

Q: Is using fetal tissue a new idea?

A: Hardly. Scientists have worked with it since the 1930s. The 1954 Nobel Prize in medicine was awarded for work with fetal tissue that led to developing a vaccine against polio. The National Institutes of Health spent $76 million on human fetal tissue research in fiscal 2014.

Q: What diseases are being studied today?

A: AIDS and muscular dystrophy, for example. Some experiment­al treatments for spinal cord injury and macular degenerati­on involve transplant­ing fetal cells into patients. And European researcher­s This Oct. 21, 1954 file photo shows Dr. Frederick C. Robbins, who, along with Dr. John Enders and Dr. Thomas Weller did work with fetal tissue that led to a vaccine against polio. are putting fetal tissue into patients’ brains to treat Parkinson’s disease.

Q: Hhow is the tissue provided?

A: It comes from hospitals and abortion clinics. Sometimes it goes directly to researcher­s, and in other cases it is handled by nonprofit organizati­ons or companies that supply researcher­s. The groups or companies can be reimbursed for expenses associated with costs like processing and storing the tissue, federal law says.

Q: Does the woman have to agree to using the tissue for research?

A: Yes, she has to give consent. And the matter can’t be raised until after she has decided to have an abortion.

Q: Can’t researcher­s just use stem cells instead?

A: Stem cells, including those obtained with adult donors, can develop into a variety of tissues in the lab. The European researcher­s in the Parkinson’s study and others hope to learn enough to use them someday for transplant tissue. Experts say stem cells have already substitute­d for fetal tissue for some purposes, but that scientists still need fetal tissue to learn basic informatio­n about how organs form, or help them simulate diseases in the test tube.

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