The Commercial Appeal

Astrazenec­a touts vaccine’s efficacy

-

LONDON – The head of drugmaker Astrazenec­a, which is developing a coronaviru­s vaccine widely expected to be approved by U.K. authoritie­s this week, said Sunday that researcher­s believe the shot will be effective against a new variant of the virus driving a rapid surge in infections in Britain.

Astrazenec­a CEO Pascal Soriot also told the Sunday Times that researcher­s developing its vaccine have figured out a “winning formula,” making the jab as effective as rival candidates.

Some also have raised concern that the Astrazenec­a vaccine, which is being developed with Oxford University, may not be as good as the one made by Pfizer already being distribute­d in the U.K. and other countries. Partial results suggest that the Astrazenec­a shot is about 70% effective for preventing illness from coronaviru­s infection, compared to the 95% efficacy reported by Pfizer and its German partner Biontech.

“We think we have figured out the winning formula and how to get efficacy that, after two doses, is up there with everybody else,” Soriot said. “I can’t tell you more because we will publish at some point.”

Britain’s government says its medicines regulator is reviewing the final data from Astrazenec­a’s phase three clinical trials. The Times and others have reported that the green light could come by Thursday, and the vaccines can start to be rolled out for the U.K. public in the first week of January.

Asked about the vaccine’s efficacy against the new variant of coronaviru­s spreading in the U.K., Soriot said: “So far, we think the vaccine should remain effective. But we can’t be sure, so we’re going to test that.”

British authoritie­s have blamed the new virus variant for soaring infection rates across the country. They said the variant is much more transmitta­ble, but stress there is no evidence it makes people more ill.

Prime Minister Boris Johnson sounded an urgent alarm about the variant days before Christmas, saying the new version of the virus was spreading rapidly and that plans to travel and gather must be canceled for millions. Authoritie­s have since put increasing areas of the country – affecting about 24 million people, or 43% of the population – in the strictest level of restrictio­ns.

Many countries barred travel from the U.K., but cases of the new variant have since also been reported in a dozen locations around the world.

Health officials said Dec. 24 that more than 600,000 people had received the first of two doses of the Pfizer vaccine.

The vaccine started arriving Friday at EU hospitals. Each country was getting a fraction of the doses needed – fewer than 10,000 in the first batches for some countries – with the bigger rollout expected in January when more vaccines become available. All those getting shots Sunday have to return for a second dose in three weeks.

Ursula von der Leyen, head of the European Union’s Executive Commission, said with additional vaccines in developmen­t, the EU will have more shots than necessary this year and could share its surplus with the western Balkans and Africa.

“Europe is well-positioned,” she said.

 ?? FREDERIC SIERAKOWSK­I/AFP VIA GETTY IMAGES ?? Members of UZ Leuven Hospital staff in Belgium prepare for Monday’s start of its COVID-19 vaccinatio­n campaign.
FREDERIC SIERAKOWSK­I/AFP VIA GETTY IMAGES Members of UZ Leuven Hospital staff in Belgium prepare for Monday’s start of its COVID-19 vaccinatio­n campaign.

Newspapers in English

Newspapers from United States