The Day

Biden saw a quick fix to increase vaccine supply. Will Pfizer go along with it?

- By MICHAEL WILNER

Washington — President Joe Biden’s coronaviru­s response team thought it had found a quick fix to increase the nation’s supply of Pfizer vaccine doses. The question is whether the pharmaceut­ical company will go along with it.

The new president took executive action last week ordering manufactur­ers to increase the production of hyper-efficient syringes, after health care workers around the country discovered last month that vials of Pfizer’s COVID-19 vaccine contained six vaccine doses instead of five — more than Pfizer had anticipate­d.

The Food and Drug Administra­tion, under former President Donald Trump, authorized the use of those extra doses. But common syringes used to extract the vaccine and to inject individual­s often had too much “dead space” in them — filled with excess vaccine meant to prevent air bubbles — that prevented collection of those extra shots.

To address the issue, Biden used powers typically reserved for wartime last week to compel the production of “low dead space” syringes, virtually guaranteei­ng the extra doses won’t go to waste.

But an agreement between Pfizer and the FDA made shortly before Biden took office may offset any supply gains the new administra­tion was hoping to achieve with the new syringes.

The president’s chief of staff, Ron Klain, said on MSNBC that the executive order “actually increases our supply effectivel­y 20%.”

But Pfizer charges the U.S. government for its vaccine by the dose — and negotiated with the FDA last month to release fewer vials after it was discovered that each vial could provide more doses than expected.

Pfizer had committed to providing the U.S. government 200 million doses, and will now count the extra doses that were discovered in its vials against that goal.

If Pfizer does not end up cutting its vials shipment, as first reported by The New York Times, then the syringes will allow health care workers to extract more doses out of each vial — increasing supply by 20%.

Biden administra­tion officials are now in talks with Pfizer on ways they can maintain the size and pace of vial deliveries. While the details of those conversati­ons are not publicly known, the White House is expressing confidence that Klain’s projection of a 20% increase in supply is still achievable with the new syringes.

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