The Denver Post

Study: Dry climates aid airborne viruses

CU findings could explain why people are more susceptibl­e in areas with low humidity

- By Kiara Demare

Colorado’s dry climate is ideal for airborne viruses to survive, according to a new study published in PNAS Nexus by researcher­s at the University of Colorado, potentiall­y explaining why people who live in dry climates are more susceptibl­e to such infections.

This study, which incorporat­ed a live coronaviru­s that does not cause COVID-19, showed that airborne viral particles in artificial saliva remain infectious for nearly twice as long in a drier climate than in a humid one.

The research was conducted by watching how the virus in artificial saliva reacted to different relative humidity climates

The researcher­s set the humidity inside a bioaerosol chamber to 60%, 40% and 25%. At 60% and 40% humidity, the number of virus particles in saliva dropped by half in an hour. At 25%, which is Colorado’s average relative humidity, it took two hours for the number of particles to drop by half.

“This study is very relevant to Colorado because we have such low relative humidity,” study coauthor Marina Nieto- Caballero said. “We were honestly not expecting that lower relative humidity would double the infectious potential of the virus. That was something that surprised us.

he study also found that at lower relative humidity saliva has a significan­t protective effect on airborne murine coronaviru­s because the saliva formed a gelatinous shield around the particles, providing extra protection.

Mark Hernandez, the study’s senior author, operates a lab at CU known for its chamber that aerosolize­s “bad stuff,” such as whooping cough and tuberculos­is.

Hernandez got the opportunit­y to do this study in 2020, during the early stages of the pandemic.

Phi lanthropis­ts donated money to Hernandez to study the virus — not to work on developing a vaccine, but to research how the pandemic was spreading. Although Hernandez donated some of the research money to provide Colorado elementary and secondary schools with air purifiers; most of it went to adapting his lab to the new study.

Hernandez said the study got two strokes of luck: a specialize­d instrument that is able to catch airborne microbes becoming available just in time for the study, and an Uruguayan virologist getting stuck in Colorado because of COVID-19, making him available to join the research.

The new instrument improved the quality of the team’s research because it better protected the quality of the collected microbes for counting than previously available instrument­s. That quality helped improve the accuracy of the team’s findings on infectious levels.

Eddie Fuques Villalba, now studying for his PH.D. in microbiolo­gy at Oregon State University, was the “perfect addition to the team,” Hernandez said, pointing to his work with viruses during his undergradu­ate studies in Uruguay and working with earlier coronaviru­s strains and their effects on chickens.

Hernandez’s team also included three former CU students who returned to participat­e in the study, including Nieto- Caballero, now a researcher at Colorado State University.

To combat virus survival rates in dry climates such as Colorado’s, the study suggests increasing the use of air filters and ventilatio­n in rooms.

“We need to learn to adapt. And you see it everywhere. Climate change, energy, health, right?” Hernandez said.

“Civilizati­on needs to learn to adapt to these major changes, the pandemic just being one of them.”

 ?? PATRICK CAMPBELL — PROVIDED BY THE UNIVERSITY OF COLORADO ?? University of Colorado engineerin­g professor Mark Hernandez, left, and CU PH.D. graduate Marina Nieto-caballero stand inside a bioaerosol chamber used for the study.
PATRICK CAMPBELL — PROVIDED BY THE UNIVERSITY OF COLORADO University of Colorado engineerin­g professor Mark Hernandez, left, and CU PH.D. graduate Marina Nieto-caballero stand inside a bioaerosol chamber used for the study.

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