The Denver Post

State’s deaths stabilized in 2022

But experts call near- record levels “unacceptab­ly high”

- By Seth Klamann sklamann@ denverpost. com

Fatal overdoses declined slightly in Colorado in 2022, newly finalized state data shows, after two years of surging deaths. But public health officials and addiction experts drew little comfort from last year’s totals, which remain near record highs amid fentanyl's growing dominance of the illicit drug supply.

“( Overdoses) evened themselves out a little bit. We have a new normal, which is terrible,” said Dr. Josh Blum, an addiction medicine physician at Denver Health. “Now we have a stable, unacceptab­ly high death rate.”

In 2022, 1,799 people fatally overdosed in Colorado, a 4% drop from 2021’ s total of 1,881, according to data from the state Department of Public Health and Environmen­t. The figures represent a bitterswee­t stabilizat­ion: A slight, one- year decline is still a reprieve after rates nearly doubled in recent years. The number of fentanylre­lated deaths — which quadrupled from 2019 to 2021 — plateaued, and methamphet­amine fatalities dipped.

Yet 2022’ s rate is still higher than any other prepandemi­c year, and fentanyl and methamphet­amine continue to fuel and dominate the crisis. Fentanyl, a potent synthetic opioid, was present in more than half of all fatal overdoses here last year. More Coloradans died after ingesting the drug in 2022 than overdosed on all drugs in 2016.

“It’s this idea that while we might be able to find some encouragem­ent if the numbers stay the same or if we do see somewhat of an increase — but the numbers are unacceptab­ly high to begin with,” said Natalee Salcedo, the community health promotion manager for the Adams County Health Department. The county has one of the highest overdose death tolls in the state, and Salcedo said recent increases have been most significan­t among Black residents.

It’s unclear what exactly prompted the flattening of deaths, six addiction and public health officials said, and they cautioned against drawing any conclusion­s of broader trends based off of one year. Sterling Mclaren, Denver’s chief medical officer, said the state may have reached a natural plateau of overdoses, as opposed to some sort of turning point.

She and other experts also noted the increased availabili­ty of harm reduction and some treatment services. The state has begun to embrace harm reduction services, intended to help keep drug users alive and healthy until they’re ready or able to seek treatment. But Blum and Salcedo called on legislator­s to go

further and to allow for safe drug- use sites, in which users can consume illicit drugs under the supervisio­n of health providers. A bill that would’ve allowed a facility to open in Denver passed the House this year, only to die in a Senate committee in late April.

Legislator­s have more thoroughly embraced more common harm reduction tools: Colorado has spent millions to distribute naloxone, which is used to reverse opioid overdoses, and lawmakers passed a bill last year to dole out free doses to a broader group of entities, including schools.

The state distribute­d more than 258,000 naloxone doses from July to March, said Sam Bourdon, the harm reduction grant program manager for the state health department. That’s more than double what was distribute­d in the year prior. Denver also distribute­s naloxone for free to city residents.

Lawmakers also set aside several hundred thousand dollars to buy fentanyl test strips, and they expanded treatment in jail settings. Thirty- one of the state’s 64 counties also have agreed to distribute fentanyl test strips, and the state has ordered more than 80,000, Bourdon said.

The pandemic’s end and the broader return to normalcy also may have contribute­d to the state’s numbers stabilizin­g. Although it increased isolation and temporaril­y limited traditiona­l treatment options, the COVID19 crisis also shepherded in positive changes to drug treatment elsewhere, Blum said: Methadone, a key medication used to treat opioid dependence, has become more available under enduring pandemicer­a rules. Telehealth has expanded, and federal regulators in December also made

it easier for physicians to give patients another opioid treatment medication.

Nationally, overdoses increased slightly in 2021, according to data from the Centers for Disease Control and Prevention. Like in Colorado, drug deaths surged across America during the pandemic, and 2022 represente­d a relative plateau after those peaks. In a statement to The New York Times, the Biden administra­tion’s drug czar attributed that stabilizat­ion to expanded treatment, improved naloxone distributi­on and law enforcemen­t efforts to limit fentanyl traffickin­g.

Policymake­rs in Colorado similarly have sought to crack down on the drug. In the same law that increased funding for naloxone and test strips, lawmakers also tightened penalties for drug users caught with the equivalent of approximat­ely 10 fentanyl pills and for dealers whose fentanyl caused a fatal overdose.

But state data shows that fentanyl continues to monopolize the drug supply, a grim if unsurprisi­ng warning that overdose rates are likely to remain high. Although it has legitimate medical uses, fentanyl has become the opioid of choice for drug manufactur­ers in recent years, given how cheap and easy it is to produce relative to heroin. It’s flooded the broader drug supply, often contaminat­ing other substances without users’ knowledge. In 2022, for instance, more than half of methamphet­amine and cocaine deaths also involved fentanyl.

Heroin, meanwhi le, largely has been replaced in the illicit market. Black tar heroin used to be the dominant opioid in Colorado, and 220 people overdosed from the drug in 2020. But that total plummeted to 62 deaths in 2022, state data shows, as cartels have prioritize­d fentanyl.

The shift has been years in the making, data and experts say. Heroin requires

a climate- dependent cultivatio­n process, and fentanyl can be made yearround in labs. Fentanyl is also 50 times more potent than heroin and represents a far more lucrative product for the cartels that dominate the illicit opioid trade. It’s cheaper for users, too: A fentanyl pill can cost as little as $ 2 to $ 3.

Thus far, Colorado hasn’t grappled with the new synthetic substances, like the animal tranquiliz­er xylazine, that are flooding parts of the East Coast. Xylazine, which isn’t an opioid, often is mixed with fentanyl and is particular­ly damaging to users who inject it. Kirk Bol of the state health department said there were four deaths involving xylazine here in 2022.

It’s unclear if 2022’ s stabilizat­ion will hold. Denver, which accounts for the largest share of the state’s overdoses, began this year “hot,” with more drug deaths than the first few months of 2022, said Ethan Jamison, a forensic epidemiolo­gist with the city’s medical examiner’s office.

He said 2023 would provide insight into what Coloradans should expect going forward.

But fentanyl’s enduring presence suggests the high rates will endure, and public health officials urged state leaders to continue embracing harm reduction approaches.

“It’s just going to make the next couple of years ( expletive),” Blum said. “It’s going to be really challengin­g for the next few years because in many cases, people who have just been introduced to opioids die before they even get a chance to get into treatment because the drug supply is so potent.”

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