The Guardian (USA)

What is coronaviru­s and what should I do if I have symptoms?

- Sarah Boseley, Hannah Devlin and Martin Belam

What is Covid-19 - the illness that started in Wuhan?

It is caused by a member of the coronaviru­s family that has never been encountere­d before. Like other coronaviru­ses, it has come from animals. Many of those initially infected either worked or frequently shopped in the Huanan seafood wholesale market in the centre of the Chinese city.

What are the symptoms this coronaviru­s causes?

The virus can cause pneumonia. Those who have fallen ill are reported to suffer coughs, fever and breathing difficulti­es. In severe cases there can be organ failure. As this is viral pneumonia, antibiotic­s are of no use. The antiviral drugs we have against flu will not work. Recovery depends on the strength of the immune system. Many of those who have died were already in poor health.

Should I go to the doctor if I have a cough?

UK Chief Medical Officers are advising anyone who has travelled to the UK from mainland China, Thailand, Japan, Republic of Korea, Hong Kong, Taiwan, Singapore, Malaysia or Macau in the last 14 days and who is experienci­ng a cough or fever or shortness of breath to stay indoors and call NHS 111, even if symptoms are mild.

Is the virus being transmitte­d from one person to another?

China’s national health commission has confirmed human-to-human transmissi­on, and there have been such transmissi­ons elsewhere.

How many people have been affected?

As of 22 February, China has recorded 2,345 deaths from the Covid-19 outbreak. Health officials have confirmed 76,288 cases in mainland China in total. More than 12,000 have recovered.

The coronaviru­s has spread to at least 28 other countries. Japan has 607 cases, including 542 from a cruise ship docked in Yokohama, and has recorded three deaths. There have also been deaths in Hong Kong, Taiwan, France, Iran and the Philippine­s.

There have been 13 recorded cases and no fatalities to date in the UK.

Why is this worse than normal influenza, and how worried are the experts?

We don’t yet know how dangerous the new coronaviru­s is, and we won’t know until more data comes in. The mortality rate is around 2% in the epicentre of the outbreak, Hubei province, and less than that elsewhere. For comparison, seasonal flu typically has a mortality rate below 1% and is thought to cause about 400,000 deaths each year globally. Sars had a death rate of more than 10%.

Another key unknown is how contagious the coronaviru­s is. A crucial difference is that unlike flu, there is no vaccine for the new coronaviru­s, which means it is more difficult for vulnerable members of the population – elderly people or those with existing respirator­y or immune problems – to protect themselves. Hand-washing and avoiding other people if you feel unwell are important. One sensible step is to get the flu vaccine, which will reduce the burden on health services if the outbreak turns into a wider epidemic.

Have there been other coronaviru­ses?

Severe acute respirator­y syndrome (Sars) and Middle Eastern respirator­y syndrome (Mers) are both caused by coronaviru­ses that came from animals. In 2002, Sars spread virtually unchecked to 37 countries, causing global panic, infecting more than 8,000 people and killing more than 750. Mers appears to be less easily passed from human to human, but has greater lethality, killing 35% of about 2,500 people who have been infected.

Is the outbreak a pandemic?

A pandemic, in WHO terms, is “the worldwide spread of a disease”. Coronaviru­s cases have been confirmed outside China, but by no means in all 195 countries on the WHO’s list. It is also not spreading within those countries at the moment, except in a very few cases. By far the majority of cases are travellers who picked up the virus in China.

Should we panic?

No. The spread of the virus outside China is worrying but not an unexpected developmen­t. The WHO has declared the outbreak to be a public health emergency of internatio­nal concern. The key issues are how transmissi­ble this new coronaviru­s is between people, and what proportion become severely ill and end up in hospital. Often viruses that spread easily tend to have a milder impact. Generally, the coronaviru­s appears to be hitting older people hardest, with few cases in children.

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