The Guardian (USA)

An app could catch 98.5% of all Covid-19 infections. Why isn't it available?

- Adrienne Matei

The world wasn’t prepared for the Covid-19 pandemic – and it still isn’t. Critical shortages of personal protective equipment and ventilator­s continue to put medical profession­als and patients at unnecessar­y risk. Meanwhile, long wait times for test results contribute to viral spread.

Yet throughout this year, promising scientific innovation­s have been developed that could help reduce deaths until everyone can get the vaccine. So why aren’t they available?

A Covid test on your smartphone

In late September, researcher­s at MIT announced that they had developed an algorithm that can accurately detect Covid-19 infections over the phone.

When participan­ts in their study produced a forced cough, MIT said their AI algorithm successful­ly detected 98.5% of Covid-19 infections with patients who have a cough and 100% of asymptomat­ic cases.

If released in the form of an app, the technology could mean instant Covid-19 testing anytime, any place.

As they wrote in their peer-reviewed article: “AI techniques can produce a free, non-invasive, real-time, anytime, instantly distributa­ble, large-scale Covid-19 asymptomat­ic screening tool to augment current approaches in containing the spread of Covid-19. Practical use cases could be for daily screening of students, workers and public as schools, jobs and transport reopen, or for pool testing to quickly alert of outbreaks in groups.”

The impact of this technology would be huge. Currently, test results can take a week to be processed. Testing delays and shortages are due to things like strains on the supply chain providing swabs and chemicals, as well as the pressures on lab technician­s processing high volumes of tests. And the test only tells you if you were positive at the time, not whether you are positive now, which can lead to a false sense of security.

A smartphone- based, instant Covid-19 test would be a game changer and would save countless lives. The developers say they intend to make the technology available as an app, pending regulatory approval, but there is no clear timeline for when it might be released to the public. (The team did not respond to a request for comment.)

A reusable N95 mask

We are all aware of the severe shortage of N95 masks – the gold standard mask for protecting people from viruses like Covid-19 – which have led to countless doctors and nurses dying because of a lack of personal protective equipment.

The reason for the shortage? Strain on the supply chain producing the melt-blown masks that relies on expensive equipment to produce.

In July, a group of researcher­s from MIT and Brigham and Women’s hospital received a flurry of media attention for their invention of a reusable, silicone-based N95 mask able to withstand repeated sterilizat­ion with high temperatur­es and bleach, making it ideal for hospital settings. This mask, which requires much less material than the standard N95 mask, could be easily manufactur­ed in the United States. And, unlike the standard N95s, could be reused 100 times. (By the end of 2020, 3M will have manufactur­ed 2bn N95 respirator­s to meet need, which will only worsen our plastic pollution crisis. A reusable mask would help avoid the mountain of waste that could end up in our oceans or our air after incinerati­on.)

According to Adam Wentworth, a research engineer working on the mask, they are still fundraisin­g to create the final prototype. Whenever the fundraisin­g is complete – there is no fixed deadline – they would have to submit it for approval by the Food and Drug Administra­tion and the National Institute for Occupation­al Safety and Health. This is a process that could take around six months, even with emergency prioritiza­tion.

At this point, a Covid-19 vaccine is projected to become widely available before the mask does. By time it does. the pandemic may likely be over.

Sewage testing for early-detection

We know that people infected with Covid may carry the virus asymptomat­ically for two weeks before realizing they are sick. That means early detection methods are essential to mitigating spread.

In May, Stat News, a medical news site, reported that testing sewage provided a promising way to detect Covid-19 cases a week early. And shortly after, Germany, Finland and the Netherland­s announced they would start sewage surveillan­ce as a way to spot Covid-19 cases. Senator Dianne Feinstein in July urged the Department of Health and Human Services to implement this technology on a national scale; however, adoption in the US has been slow.

Several universiti­es, including MIT, are already using wastewater testing to stay ahead of outbreaks on campus – the method helped successful­ly stem an outbreak at a University of Arizona dorm in August – but most communitie­s are still not benefiting from a simple and effective early-detection tool that is proven to work.

We know that we are entering the deadliest phase of the pandemic, with cases and fatalities exceeding previous peaks in the spring. With vaccines now being rolled out in the UK, China, Russia and other countries at record speed, the question is whether any of these technologi­es will be employed when they are most critical – namely now – or whether they will become widespread only as we emerge out of this global pandemic. One hopes that “warp speed” might not be limited to the vaccine but other technologi­es, too. But it doesn’t look promising.

 ?? Photograph: Westend61/Getty Images ?? ‘If released in the form of an app, the technology could mean instant Covid-19 testing anytime, any place.’
Photograph: Westend61/Getty Images ‘If released in the form of an app, the technology could mean instant Covid-19 testing anytime, any place.’
 ?? Photograph: MIT ?? Mannequin wearing a reusable silicone N95 mask.
Photograph: MIT Mannequin wearing a reusable silicone N95 mask.

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