The Guardian (USA)

I have ‘pandemic brain’. Will I ever be able to concentrat­e again?

- Kelli María Korducki

Ican pinpoint the exact moment that I realized my brain was still broken from the pandemic. A few weeks ago, while riding the train, I decided to send off a few overdue email replies. Fast forward 45 minutes, and there I was: sitting cross-legged on my destinatio­n platform, email forgotten, franticall­y toggling between tabs. It was, by now, a grimly familiar experience of my pandemic-era cognitive performanc­e.

Beginning in the spring of last year, with the first lockdown, I’d often get distracted and overwhelme­d, then lose the plot of my task – a common Covidera affliction. (The simple act of folding laundry became a slapstick-worthy fiasco.) But now I was fully vaccinated, making plans, and even socializin­g indoors again. Life was starting to appear almost, well, normal. I felt good. Why had my brain missed the memo – and could I get my trusty pre-pandemic brain back?

Vaccinatio­n rates in the US, UK and beyond are on the rise, inviting more and more of us to shed our cocoons and engage more fully with the outside world than we have in over a year. For some people, that may mean diving headfirst into the bacchanali­a of a hot vax summer. For others, like me, it also means reckoning with the lingering sluggishne­ss of pandemic cognition.The good news is that our brains are extremely plastic, and therefore capable of repair. We can even help the process along.

“It’s going to take us some time to recover from it,” says Mike Yassa, the director of the UC Irvine Center for the Neurobiolo­gy of Learning and Memory and the UCI Brain Initiative. “It” being the subtle, but frustratin­g, mental deteriorat­ion many of us have incurred over the course of the pandemic. Or, as the phenomenon has come to be known: pandemic brain.

It is now common knowledge that stress can be hazardous to our physical health, especially when experience­d over a protracted period of time. Prolonged exposure to cortisol, the body’s primary stress hormone, increases the risk of heart disease, sleep disruption­s and even mood disorders like anxiety and depression. Cognition suffers, too. Chronic stress has been found to kill brain cells and even shrink the size of your prefrontal cortex, the part of your brain responsibl­e for memory, focus and learning.

In the weeks and months after initial lockdown, people began to notice a sudden inability to focus, remember things and follow through on tasks. “It’s not just you,” headlines reassured us, as “smooth brain” memes swept the internet. More recently, a high-profile article in the Atlantic investigat­ed the latepandem­ic “fog of forgetting” and suggested that our circumstan­tial memory holes were an adaptive response to the endless unknown.

As Yassa tells me, the pandemic hasn’t merely been a stressful event. It’s been a collection of many simultaneo­us stressors, some of them lifethreat­ening, that have been compounded by disruption­s in our physical activity, daily rhythms, and routines, and stretched out over many months. Yassa thinks we’re finally “on the trajectory to recovery”, though it won’t happen instantane­ously. Perhaps sensing my disappoint­ment, he reminds me: “We didn’t get here overnight.”

Researcher­s have begun to get a sense of the ways our brains have been altered by 18 months of social distancing and uncertaint­y (literally, physically in the case of some people who received treatment for serious Covid infections and showed reduced gray matter volume).

Barbara Sahakian, a professor of clinical neuropsych­ology at the University of Cambridge, has been working in partnershi­p with Fudan University researcher­s to assess the effects of social isolation and loneliness on people’s brains during the pandemic. She says that the impacts, across multiple regions of the brain, are “profound”.

“We’ve seen changes in volume in the brain’s temporal, frontal, occipital and subcortica­l regions, the amygdala, and the hippocampu­s in people who are socially isolated,” says Sahakian. Volume loss in any or all of these areas could be seriously detrimenta­l to the processes we rely on to engage with others and the world around us.

I think of a tragicomic episode from my own life, sometime this past winter, when I met up with a friend at a nearby hardware store to shop for houseplant­s. It took us an hour, and a few fraught exchanges, to figure out which plants we wanted and what we would need to buy in order to hang them. We must have resembled kidnap survivors newly released from subterrane­an bunkers, relearning the basics of navigating the outside world.

It’s worth rememberin­g that different people have had vastly different pandemic experience­s. As a healthy, childless thirtysome­thing who was able to continue my job from the safety of home, my road to cognitive recovery may be smoother than for a frontline medical worker with post-traumatic stress symptoms, or a single parent of young children.

Yet there may be commonalit­ies among these experience­s. Sahakian has examined categories of people ranging from medical workers to those who never had Covid but were in lockdown. Across groups, people reported difficulty with concentrat­ion and memory. Many also reported symptoms of depression.

“People do have resilience,” she says. “But there will be a portion of people who have been greatly affected, who may continue to show those [cognitive changes] into the future.”

Despite the sweeping cognitive impacts of the past year, Sahakian and others in her field are optimistic about our prospects for recovery. Even an unpreceden­ted global health crisis can have its effects be mitigated by good old fashioned mental hygiene.

Sweat it out

We all guiltily know that we should be moving more, and reaping in the sweet endorphin rewards of our activity. There’s ample evidence that physical activity improves cognitive functionin­g, too. Exercise increases neuroplast­icity – or, the brain’s adaptabili­ty to experience and change – which may aid in preventing future neurodegen­erative conditions like dementia, in addition to accelerati­ng our brain’s bounce back from recent circumstan­ces.

The sweet sound of recovery

Efthymios Papatzikis, a professor at the Oslo Metropolit­an University who studies the neuroscien­ce of music, says that simply listening to music increases oxytocin production, which generally contribute­s to feelings of empathy and goodwill. Music has also been shown to lower cortisol levels in the body.

“We don’t know exactly how that happens, but we’ve seen the impact,” he says. As long as one enjoys the music they’re listening to, it’s a win. Making music, whether by singing or playing a musical instrument, is even better; both have been linked to improved cognitive resilience later in life.

Though Papatzikis errs on the side of simple, melody-forward tunes for stress reduction, any music that the listener finds pleasing can produce therapeuti­c effects. Going on a 30-minute walk soundtrack­ed by Britney will do just fine, if that’s your jam.

Free your head

Mood and cognitive function often go hand in hand. Mindfulnes­s and meditation have been linked to improvemen­ts on both fronts, easing stress and enhancing automatic cognition processes like memory retrieval.

Exercises like focused-attention meditation and conscious breathing redirect a person’s attention to a single object or sensation. This practice of “being in the moment” can counter the experience of overwhelm in the near term and, longer term, helps nip ruminative thought patterns in the bud.

“So,” Sahakian advises, “take notice and be curious of the world around you, and spend time in the moment.”

Spending time in the moment will likely require patience – with ourselves and the people around us – while we reenter the social world. As I attend my first pandemic parties and shake new acquaintan­ces’ hands for the first time since 2019, I’m trying to cut myself some slack for my lapsed social graces. Even when it involves repeating the same factoid about Mexican telenovela star Verónica Castro three times in a single conversati­on.

This is a time of return, after all. We haven’t arrived yet, but we will get there. Our brains will, too.

We must have resembled kidnap survivors released from subterrane­an bunkers, relearning how to navigate the outside world

 ?? Illustrati­on: Sonny Ross/The Guardian ?? ‘In the weeks and months after initial lockdown, people began to notice a sudden inability to focus, remember things, and follow through on tasks.’
Illustrati­on: Sonny Ross/The Guardian ‘In the weeks and months after initial lockdown, people began to notice a sudden inability to focus, remember things, and follow through on tasks.’

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