The Guardian (USA)

Covid reinfectio­ns: why are they being included in UK case numbers?

- Nicola Davis Science correspond­ent

With reinfectio­ns now included in the daily Covid case numbers for most countries in the UK, we take a look at why the shift matters.

How are reinfectio­ns counted?

Covid reinfectio­ns can involve either the same or a different variant. Since 31 January reinfectio­ns have been included in the daily reported case numbers for England and Northern Ireland. Reinfectio­ns are expected to be included for Scotland in weeks, and were already included in figures for Wales.

While the definition of a reinfectio­n for England and Northern Ireland is a positive specimen at least 90 days after the last one, for Wales that gap is at present defined as at least 42 days.

The UK Health Security Agency (UKHSA) says a gap of at least 90 days captures the majority of reinfectio­ns, while excluding those for whom fragments of the virus are detected for a long period of time. The agency says the interval will be standardis­ed across

UK countries in the coming weeks. reinfectio­ns have

How many there been?

According to UKHSA data for England, at present, possible reinfectio­ns account for about 10% of new cases reported each week. An estimated 532,570 reinfectio­n episodes have been identified in England between the beginning of the pandemic and 23 January this year. This is a small figure compared with the 14.2m cases believed to be first infections.

However, these figures are based on people who have come forward for a Covid test. Not all those with a Covid infection do so – while during the first wave, access to tests was very limited, meaning both cases and reinfectio­ns were underestim­ated.

Are some people more likely to be reinfected than others?

According to data from the Office for National Statistics (ONS) – which uses an episode interval of 120 days, or four consecutiv­e negative tests, in its definition of a reinfectio­n – unvaccinat­ed people are about twice as likely to have a reinfectio­n as those who had their second Covid jab between 14 and 89 days ago. Reinfectio­n also appears to be more likely among people whose previous infection involved a lower quantity of the virus, and among those who had their Covid jabs more than 90 days ago.

But other factors are also at play. “Reinfectio­n is a result of a combinatio­n of exposure and risk once exposed,” said Prof Rowland Kao, an epidemiolo­gist at the University of Edinburgh and member of the modelling group Spi-M, adding that the risk once exposed can be affected by elements such as the time since last infection, as well as past health.

“It seems that a lot of those factors do come together to potentiall­y in

crease observed reinfectio­n rates – so many of the people who are in highexposu­re jobs also are more likely to have health issues because the factors allied to deprivatio­n are related to both,” he said.

Has Omicron had an effect on reinfectio­ns?

Yes. According to ONS data, the risk of reinfectio­n was 16 times higher when Omicron became dominant in the UKcompared with the period when Delta dominated. That is not surprising: the variant has been found to be able to dodge the body’s immune responses to a significan­t degree.

However, many of the new reinfectio­ns would have been among people who had Delta, or another variant, previously, given that the first Omicron cases were only picked up in the UK in late November. The question remains how well those who have had Omicron are protected against a second Omicron infection, or infections with new variants.

 ?? ?? Commuters at Waterloo station in London during morning rush hour this week. Photograph: WIktor Szymanowic­z/NurPhoto/Rex/ Shuttersto­ck
Commuters at Waterloo station in London during morning rush hour this week. Photograph: WIktor Szymanowic­z/NurPhoto/Rex/ Shuttersto­ck

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