The Guardian (USA)

Junk science is cited in abortion ban cases. Researcher­s are fighting the ‘fatally flawed’ work

- Jessica Glenza

The retraction of three peer-reviewed articles prominentl­y cited in court cases on the so-called abortion pill – mifepristo­ne – has put a group of papers by anti-abortion researcher­s in the scientific limelight.

Seventeen sexual and reproducti­ve health researcher­s are calling for four peer-reviewed studies by anti-abortion researcher­s to be retracted or amended. The papers, critics contend, are “fatally flawed” and muddy the scientific consensus for courts and lawmakers who lack the scientific training to understand their methodolog­ical flaws.

While some papers date back to 2002, the group argues that now – in the post-Roe v Wade era – the stakes have never been higher. State and federal courts now routinely field cases on near-total abortion bans, attacks on in vitro fertilizat­ion and attempts to give fetuses the rights of people.

“When we saw the meta-analysis presented again and again and again – in the briefs to the Dobbs case” that overturned Roe v Wade “and state cases” to restrict abortion, “the concerns really rose,” said Julia Littell, a retired Bryn Mawr professor and social researcher with expertise in statistica­l analysis.

A meta-analysis is a kind of research that uses statistica­l methods to combine studies on the same topic. Researcher­s sometimes use these analyses to examine the scientific consensus on a subject.

Littell was “shocked” by a paper that said women experience dramatic increases in mental health problems after an abortion – primarily because of the paper’s research methods.

Of the 22 studies cited by the meta-analysis, 11 were by the lone author of the paper itself. The meta-analysis “failed to meet any published methodolog­ical criteria for systematic reviews” and failed to follow recommenda­tions to avoid statistica­l dependenci­es, according to a criticism published in the British Medical Journal (BMJ).

Large scientific bodies have found no evidence to suggest abortion causes increases in mental health problems. The best predictor of a woman’s mental health after an abortion is her health before. What’s more, there is substantia­l evidence that women who are denied a wanted abortion suffer both mental and financial harms.

From the time it was published, this 2011 meta-analysis has drawn consternat­ion. Still, it remains in the scientific record in a dispute that the 17 authors of the BMJ criticism, including Littell, say goes beyond mere scientific disagreeme­nt.

The paper has been cited in at least 24 federal and state court cases and 14 parliament­ary hearings in six countries.

Dr Chelsea Polis, a reproducti­ve health scientist in New York City, who helped gather the group of academics, says her “concerns with the meta-analysis on abortion and mental health published … are based on it being, in my profession­al opinion, egregiousl­y methodolog­ically flawed”.

The researcher who wrote the article, Priscilla Coleman, a retired professor from Bowling Green State University in Ohio, has responded to calls for retraction­s with legal threats and descriptio­ns of conspiracy. She said calls for retraction were “an organized effort to cull profession­al literature and remove studies demonstrat­ing abortion increases risk of mental health problems to impact the legal status of abortion”.

Since the supreme court overturned the constituti­onal right to abortion and allowed 21 states to severely restrict or ban the procedure, a series

of retraction­s and investigat­ions show how the scientific community is slowly beginning to re-evaluate work cited in these court cases.

“We’re seeing claims made with legal force behind them, and that’s causing people to look at a lot of this research in a different way,” said Mary Ziegler, a professor of law at the University of California Davis, and an expert on the history of reproducti­on.

A second author whose work is at the center of the BMJ critique is David C Reardon, a longtime abortion opponent. A 2002 study by Reardon, also published in BMJ, is now under investigat­ion.

BMJ said in a statement that the “issue remains under considerat­ion by our research integrity team”, and that their final decision would be made “public once we have completed our internal process”.

Reardon trained as an engineer, but found his calling in research that claimed a connection between abortion and poor mental health. He founded the Elliot Institute in Illinois, an openly anti-abortion non-profit, to pursue that research.

Today, Reardon is affiliated with the Charlotte Lozier Institute, funded by one of the most powerful anti-abortion campaign organizati­ons in the US, Susan B Anthony Pro-Life America. Reardon also co-authored two of the articles that were retracted before supreme court hearings, both by a colleague at the Lozier Institute. Reardon did not respond to multiple requests for comment.

According to analyses of the literature and experts such as Julia Steinberg, an associate professor of family science at the University of Maryland School of Public Health and a co-author of a recent critique of these studies in BMJ, the science is not in dispute. The “rates of mental health problems for women with an unwanted pregnancy were the same whether they had an abortion or gave birth”, an analysis by the UK’s National Collaborat­ing Center for Mental Health found in 2011. That review was cited as one of the best by the US National Academies of Sciences, Engineerin­g and Medicine, in its own 2018 review of the issue.

Other reviews, such as one from 2009 by the American Psychologi­cal Associatio­n, found evidence “did not support the claim that observed associatio­ns between abortion and mental health problems are caused by abortion per se”.

“One can be pro-choice or pro-abortion or anti-abortion, but still understand what the science says with respect to abortion and mental health,” said Steinberg.

Although matters of scientific integrity may seem academic, they can have concrete impacts on policy in the US post-Roe.

One of the few cases of scientific retraction­s to break through to the wider public was in Texas, where a federal court relied heavily on two studies in a decision to invalidate the approval of mifepristo­ne – better known as the “abortion pill”.

The case was appealed all the way to the supreme court, where it was heard in March in oral arguments in Alliance for Hippocrati­c Medicine v FDA. Just weeks before the justices were set to hear the case, and as nearly the entire scientific community screamed about the “junk science” at its heart, the heavily cited studies were retracted by Sage Publicatio­ns. Even so, the article’s claims remained in briefs before the court, and were cited as evidence by one of the most conservati­ve justices, Samuel Alito.

Like Reardon, Coleman also recently had a paper retracted, this one in Frontiers in Psychology in 2022. The journal said publicly that the paper “did not meet the standards for publicatio­n”. Notably, one of the paper’s reviewers also worked at the Lozier Institute. Coleman unsuccessf­ully sued the journal over its decision to retract. The court ruled against Coleman in March 2023, Frontiers told the Guardian.

Coleman’s 2011 meta-analysis, published in the British Journal of Psychiatry, was also involved in a heated retraction fight in the UK. The first calls for retraction of the article came soon after it was published in 2012.

It was again brought to journal editors in 2022 after the BJP establishe­d a research integrity group. “Motivated by strong agreement with” the importance of scientific integrity, said Polis, “I led a group of 16 scholars to summarize and submit our concerns, again, about the Coleman meta-analysis to BJP.”

In response to these concerns, the BJP establishe­d an independen­t panel of experts to investigat­e. The panel recommende­d Coleman’s article be retracted, but was overruled by the Royal

College of Psychiatri­sts, the profession­al associatio­n that publishes the BJP. The move prompted members of the independen­t panel and some editorial board members to resign.

Later reporting that appeared in the BMJ included panel members saying they believed the college declined to retract because they may not have had comprehens­ive legal cover in the United States. Coleman threatened to sue – twice – according to letters obtained by the BBC.

Although Coleman denied that her legal threats contribute­d to the BJP’s decision not to retract her study, she said help from attorneys had been important to defending her work.

“I have spent the last two years vigorously defending three of my own articles and without the financial means to hire highly competent lawyers and the time and opportunit­y to write lengthy rebuttals, the impact could have been very damaging,” said Coleman.

The Royal College of Psychiatri­sts responded to inquiries from the Guardian by sending a 2023 statement on its decision. That statement read, in part: “After careful considerat­ion, given the distance in time since the original article was published, the widely available public debate on the paper, including the letters of complaint already available alongside the article online, and the fact that the article has already been subject to a full investigat­ion, it has been decided to reject the request for the article to be retracted.” The statement added: “We now regard this matter as closed.”

Coleman has also defended her work when she testified in US courts, including in a Michigan hearing in which she said her study was “not retracted”.

Steinberg said: “That’s what’s really infuriatin­g.”

Coleman “hasn’t even had to admit that she made an error”, she added.

Researcher­s also called for retraction of a 2009 article in the Journal of Psychiatri­c Research by Coleman and the anti-abortion activists Catherine Coyle and Vincent Rue. This article too has been under fire for years and even publicly debunked.

In spite of apparent flaws, Coleman included this 2009 article in her metaanalys­is, which critics say compounds the errors.

Additional­ly, authors of the BMJ critique called for a 2005 article in the Journal of Anxiety Disorders by Coleman, Reardon and a Florida State University psychology professor, Jesse Cougle, to be accompanie­d by an expression of concern.

Ivan Oransky, one of the founders of the Retraction Watch blog, said that although retraction­s had become more common, they were nowhere near common enough to correct the scientific record. About one in 500 papers are retracted today, but perhaps as many as one in 50 ought to be, he said.

“All it does is further throw into question what the heck value these multibilli­on-dollar publishing companies are adding,” said Oransky. For critics of the scientific publishing industry, like Oransky, the response shows how flawed studies cited by courts are a “symptom” of problems with publishers, rather than a failure of courts.

To Littell, the solution is in plain sight: “We really need to be publishing fewer papers, better work, better science.”

But it has been a long road to get here. Avenatti, once a staunch critic of Trump and who briefly toyed with running for the Democratic presidenti­al nomination, now describes the four separate criminal cases against Trump as “absolute overkill” and said he is willing to testify for the defense in the current case.

Avenatti told Fox News Digital last week that “a group of individual­s” had decided that “they don’t want to leave it to ‘the little guy’” to decide the next president.

“I certainly see [Trump] as a victim of the system, and that’s something that I never thought I would say,” he said.

There has long been media speculatio­n that Avenatti is simply seeking the chance of a presidenti­al pardon if Trump is returned to the White House in November.

As for Cohen, he has claimed to be a changed man in congressio­nal testimony, TV interviews, two books, a podcast and in court testimony (which a judge said amounted to perjury).

“I am the canary in the coalmine for millions of Americans mesmerized by Trump,” Cohen said on his podcast, Mea

Culpa. He said he hoped that speaking out would serve as a “way to right some of the many wrongs I committed at his behest”.

Like Avenatti, Cohen, too, is a convicted felon, and served a prison sentence after pleading guilty to eight counts of criminal tax evasion and campaign-finance violations – including on a $100,000 payment received on the sale of a Florida property, $30,000 in profit made from brokering the sale of an Hermès Birkin handbag, more than $200,000 in consulting income earned from an assisted living company, and failing to report more than $4m on income from a New York yellow-cab medallions scheme.

Senior Democrats in Congress have voiced concern that a man like Cohen, who once said he would “take a bullet” for Trump, presents an uneven claim for redemption.

“I think his willingnes­s to speak out and to incur the wrath of Trump world is significan­t,” the congressma­n Adam Schiff told the Washington Post last week, but said Cohen “would still be a loyal Trump soldier if Trump hadn’t been willing to discard him like a piece of bad fruit”.

A federal judge overseeing Cohen’s request to be released from court supervisio­n said last month that the testimony Cohen had given in Trump’s previous civil trial showed he had either lied when he pleaded guilty to tax fraud in 2018 or perjured himself when he “repeatedly and unambiguou­sly” denied it at Trump’s fraud case.

Trump, meanwhile, has repeatedly risked violating a court-imposed gag order that prevents him from disparagin­g witnesses, including Cohen, and virtually anyone involved in the case except the judge and the district attorney.

“Michael Cohen is a convicted liar, and he’s got no credibilit­y whatsoever,” he railed last week in an interview with Philadelph­ia radio station WPVI.

Still, a disbarred lawyer serving as a turncoat witness in a criminal trial is uncommon, says Michael S Ariens, author of The Lawyer’s Conscience: a History of American Lawyer Ethics.

“Ordinarily, lawyers don’t get involved as deeply into these illicit activities as you see in Cohen’s case and Avenatti’s case. Lawyers can do things the public finds pretty distastefu­l, but they normally stick to distastefu­l activities rather than criminal,” Ariens said.

“It started as distastefu­l and worked its way to illicit.”

The seated jury in the hush-money trial contains two lawyers, probably a purposeful component of the two opposing jury selection teams. Ariens says having lawyers on a jury could lead to a few things. While they are likely to do their best to follow the instructio­ns, they’re also “often harshly critical of other members of their profession, both in terms of the prosecutio­n and defense team in assessing their abilities, but in this case the lawyers who are also witnesses”.

“That could help the defendant Donald Trump in this because there might be less of a sense of scoring political points and more of this is a legal case, let’s follow the law,” Ariens said.

Striking, too, is the number of lawyers who have become embroiled in Trump’s other alleged crimes. In the Florida classified documents case, the attorney-client privilege of the Trump lawyer Evan Corcoran was waived. He was forced to testify before a grand jury, after the presiding judge found that Corcoran’s legal work may have been used in the commission of a continuing crime.

In the Georgia elections interferen­ce case, special prosecutor Nathan Wade was forced to step down after a judge found that a romance between him and the Fulton county district attorney, Fani Willis, had created an “appearance of impropriet­y”. In the January 6 case, the Trump justice department lawyer Jeffrey Clark was called to testify before a congressio­nal committee, and Clark also faces criminal charges in the Georgia case.

The only comparable time when so many lawyers have been converted into criminal defendants was Watergate, Ariens points out.

Converting lawyers into turncoat or cooperatin­g witnesses, or into criminal defendants, could have two outcomes, says Ariens. In one, the public will says, “well, what did you expect from lawyers – we knew they were untrustwor­thy and use their knowledge to help their clients and that’s the kind of system we have”.

In the other, Ariens says, the public may conclude, that, yes, there were crooked lawyers involved “but there were other lawyers who wanted to do justice in the criminal system who actually helped create the opportunit­y for sussing them out and prosecutin­g them under the law”.

 ?? Photograph: NurPhoto/Getty Images ?? Tablets of mifepristo­ne and misoprosto­l. Two studies at the heart of the mifepristo­ne case heard at the supreme court were retracted.
Photograph: NurPhoto/Getty Images Tablets of mifepristo­ne and misoprosto­l. Two studies at the heart of the mifepristo­ne case heard at the supreme court were retracted.

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