The Mercury News

Senator agitates for increased pharma scrutiny

- By Matthew Perrone

WASHINGTON — A high-ranking Senate Democrat is pushing for more answers on why doctors and patient advocates with financial ties to the pharmaceut­ical industry came to serve on a panel that advises the federal government on pain issues.

Sen. Ron Wyden says he is “even more concerned” about these apparent conflicts of interest after receiving a response from the National Institutes of Health, which vetted and selected the panel members.

In a letter sent Thursday to the Obama administra­tion’s top health official, Wyden requests a series of documents related to the pain panel, including financial disclosure forms filled out by its members.

A spokesman for the Department of Health and Human Services, which oversees NIH, said in a statement, “we will be reviewing the letter and responding in a timely manner.”

The panel attracted attention late last year when several members bashed a federal plan to recommend doctors reduce prescribin­g of painkiller­s used to treat chronic pain, such as OxyContin and Percocet. The guidelines were ultimately issued in March by the Centers for Disease Control and Prevention, despite the panel’s objections.

The Associated Press reported earlier this year that nearly half of the nonfederal members on the panel had apparent ties to pharmaceut­ical companies or advocacy groups that receive funding from drugmakers.

The panel includes federal officials and outside doctors and patient representa­tives.

“I’m going to continue to demand accountabi­lity to ensure the manufactur­ers of these powerful prescripti­on drugs aren’t having an undue influence on policies designed to reduce their usage,” said Wyden, who is the highest-ranking Democrat on the Senate Finance Committee, in a statement.

Two panelists work for the Center for Practical Bioethics, a Missouri non-profit which receives funding from drugmakers, including OxyContin-maker Purdue Pharma, which donated $100,000 to the organizati­on in 2013.

One panelist holds a chair at the center created by a $1.5 million donation from Purdue.

The other has received more than $8,660 in speaking fees, meals, travel accommodat­ions and other payments from pain drugmakers, including Purdue, according to federal records.

In total, the Center for Practical Bioethics says drug and device companies have contribute­d about 5 percent of its funding in the last four years, though the center does not publish specific donation amounts.

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