The Mercury News

Where is the research money for coronaviru­s?

- By Julia Schaletzky Julia Schaletzky, a Harvardtra­ined bioscienti­st, is the director of the H. Wheeler Center for Emerging and Neglected Diseases at UC Berkeley.

With President Trump’s signature on the enormous $2.2 trillion stimulus package to provide relief to about anyone who is losing business or income due to COVID-19, one thing is notably absent from the discussion: research funding.

Despite the strong groundswel­l of researcher­s and scientists coming together to innovate and provide lasting solutions to this crisis, I am not aware of a laboratory that has actually received federal funding for COVID-19 research. We are 11 weeks into this aggressive, rapidly spreading pandemic, but we have not received funds to study transmissi­on dynamics or the biology of the virus to develop badly needed vaccines, therapeuti­cs or rapid diagnostic­s.

Academic research is fueled by the grant system, a notoriousl­y slow and bureaucrat­ic way of paying for salaries, reagents and supplies, administer­ed through the National Institutes of Health and other government institutio­ns. While with a lot of fanfare, “rapid emergency funding for COVID-19” was announced and legislatio­n has already passed allocating funding to the National Institute of Allergy and Infectious Diseases and others, we are left to discover somewhere in the fine print that we don’t qualify, or the amount funded is very small, or the “rapid turnaround” for review alone can take up to 60 days, or extensive preliminar­y data is needed on the project, data that no one could generate because this virus wasn’t known three months ago.

Webinars about funding opportunit­ies crash because too many dial in. NIH program officers are inundated with requests and can’t respond. Funding for COVID-19 diagnostic testing is supposed to be provided by the Centers for Disease Control and Prevention, yet that money is nowhere to be seen, leaving us to order supplies for patient testing yet again with philanthro­pic donations and recruit volunteers to collect samples and run machines.

The National Science Foundation is proud to have so far released 10 small COVID-19 grants for the entire nation, $2 million worth in total. Let’s compare this to the $58 billion planned to be allocated to airlines alone in the current stimulus package. One can’t help but wonder, who will develop an effective drug or a working vaccine for a disease that is threatenin­g the globe? Airlines? Hotels? Cruise ship companies?

At the University of California, we are working on setting up diagnostic testing, study outbreak dynamics, and are pursuing several novel therapeuti­c programs to combat COVID-19 infection. With the best and brightest from other fields coming into the fold, we have a once in a lifetime opportunit­y to develop antivirals and vaccines that might end coronaviru­s pandemics once and for all. However, it won’t happen without funding and support.

We urgently need centralize­d, unbureaucr­atic seed funding distribute­d directly through universiti­es that allow immediate action on COVID-19 projects so that no time is wasted writing proposals and waiting for funding agency decisions in this rapidly spreading outbreak. Several months later, we could assess which projects do well and which should be discontinu­ed.

This model would allow us to become more innovative, enable us to start a full-blown attack on COVID-19 without delay, with a minimum amount of waste and the possibilit­y of a large return on investment. All this could happen on pennies on the dollar relative to the stimulus proposed for airlines and hotels. Instead of just putting out fires everywhere, we need to fix the root cause of the problem and catch the arsonist.

 ??  ?? UC Berkeley bioscienti­st Julia Schaletzky, right, is asking why the federal government isn’t making more money available for research to fight COVID-19.
UC Berkeley bioscienti­st Julia Schaletzky, right, is asking why the federal government isn’t making more money available for research to fight COVID-19.

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