The Mercury News

New study reveals the data that helped prompt Bay Area lockdown

Early testing in Santa Clara County suggested a crisis

- By Marisa Kendall mkendall@ bayareanew­sgroup.com

A unique, early coronaviru­s testing program in Santa Clara County helped officials recognize the crisis and respond with the country’s first shelter-in-place order, according to a new report from the U.S. Centers for Disease Control and Prevention.

But just as experts say it highlights the importance of early and widespread testing, the study also underscore­s how the state comes up short in its testing capacity.

On March 5 — when Santa Clara County had reported just 21 cases of COVID-19 and wasn’t testing anyone unless the person had traveled abroad to a coronaviru­s hotspot or had been in contact with a known infected person — health officials began their “sentinel surveillan­ce” study. Spooked by the first known case of the virus spreading by community transmissi­on in the county a week earlier, they decided to hunt for more such cases.

From March 5 to March 14, officials began taking data from four urgent care centers in Santa Clara County. The researcher­s looked at 226 patients who complained of respirator­y symptoms but had

no travel history to coronaviru­s hotspots or known contact with an infected person.

Of those, 23% tested positive for influenza. Among the patients who tested negative for influenza, the researcher­s had the capacity to test just 79. Of those, 11% — or nine patients — tested positive for the coronaviru­s.

Based on that data, the researcher­s estimated that 8% of all patients with respirator­y symptoms at the four clinics had COVID-19.

“I think this is something that health department­s across the country are interested in because it helps inform what is going on in their communitie­s. But it does take resources and time to set up.”

— Dr. George Han, deputy health officer for Santa Clara County and the senior author of the CDC report

That was a startling finding.

“It’s important because it shows that there is transmissi­on of the disease in the community, and that the disease was perhaps more widespread than previously understood,” said Dr. George Han, deputy health officer for Santa

Clara County and the senior author of the CDC report. “And because of that, we were able to use that data as one piece of data to inform our decision about making recommenda­tions and orders to the general public.”

Coupled with the evergrowin­g number of coronaviru­s

cases reported, the new data spurred county officials to act. On March 16 — just two days after the study ended — Santa Clara County joined five other Bay Area localities to issue the first-inthe-nation stay-at-home order. Three days later, Gov. Gavin Newsom made it a statewide mandate.

But because testing capacity was so limited, the Santa Clara County researcher­s could not test every patient who fit their criteria. Instead, they tested the first five to 10 patients who fit their criteria each day, and then stopped. The result was a

small study with a limited sample size.

“That’s why we need a national strategy to ramp up the production of testing materials and testing kits,” Han said, “so that we can get a better handle on controllin­g this epidemic.”

Brian Schwartz, a professor of medicine in the division of infectious diseases at UCSF, agrees.

The study was “reinforcin­g the idea that we have not been doing enough testing, and we haven’t been doing it early enough,” he said. “And when we do it, we pick up cases.”

Han hopes other communitie­s around the country, especially those that haven’t yet seen many confirmed COVID-19 cases, will run similar “sentinel surveillan­ce” programs.

Santa Clara County is discussing conducting another similar study in partnershi­p with other Bay Area jurisdicti­ons.

“I think this is something that health department­s across the country are interested in because it helps inform what is going on in their communitie­s,” Han said. “But it does take resources and time to set up.”

Newspapers in English

Newspapers from United States