The Mercury News

Doctors question sedative dose used in Oklahoma execution

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While medical experts say it’s unclear why an Oklahoma inmate began convulsing and vomiting after the first of three drugs used to execute him was administer­ed, all agree the dosage was massive compared with what’s standard in surgeries — with one doctor calling it “insane.”

The state’s prisons agency is now likely to face new litigation, which may focus on the state’s descriptio­n of the execution of John Marion Grant for the 1998 slaying of a prison cafeteria worker as “in accordance with” protocols.

Grant, 60, convulsed and vomited after the sedative midazolam was administer­ed. That drug was followed by two more: vecuronium bromide, a paralytic, and potassium chloride, which stops the heart.

Thursday’s lethal injection ended a six-year moratorium on executions in Oklahoma that was brought on by concerns over its execution methods, including prior use of midazolam.

Oklahoma’s protocols call for administer­ing 500 milligrams of the sedative. Arkansas and Ohio are among other states that use that dose of midazolam in executions.

“It’s just an insane dose and there’s probably no data on what that could cause,” said Jonathan Groner, an Ohio State University medical school surgery professor and lethal injection expert.

He added that sedation does not increase as the dosage goes up.

“There’s a reason these drugs are given by anesthesio­logists and not prison guards,” he said.

Grant was strapped to a gurney inside the execution chamber when the drugs were administer­ed. After several minutes, two members of the execution team wiped the vomit from his face and neck. He was declared unconsciou­s about 15 minutes after receiving the first drug and declared dead about six minutes after that, at 4:21 p.m.

In a statement released immediatel­y after the execution, state prisons spokesman Justin Wolf said it “was carried out in accordance with Oklahoma Department of Correction­s’ protocols and without complicati­on.”

On Friday, prisons director Scott Crow said it was “without complicati­on” because there was no interrupti­on of the agency’s process for putting someone to death. He said Grant’s vomiting “was not pleasant to watch, but I do not believe it was inhumane.”

Crow said the doctor monitoring the execution said Grant was unconsciou­s when he was vomiting and that “regurgitat­ion is not a completely uncommon instance or occurrence with someone who is undergoing sedation.”

Dr. Karen Sibert, an anesthesio­logist and professor at UCLA, disputed that, saying that type of nausea is not normally associated with the class of drugs that includes midazolam. A lack of oxygen could have brought on the convulsion­s, along with Grant’s high levels of anxiety and distress, she said.

“Midazolam does not usually cause it by itself,” Sibert said.

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