The Middletown Press (Middletown, CT)

Alexion completes deal to acquire privately held biotech

- By Luther Turmelle luther.turmelle@hearstmedi­act.com

Alexion Pharmaceut­icals, the bio-pharmaceut­ical company that was headquarte­red in New Haven until earlier this year, has completed its acquisitio­n of a Bostonbase­d drugmaker.

The deal to acquire Syntimmune closed on Friday, according to Alexion officials. The $1.2 billion deal was announced in late September.

Syntimmune is a privately held biotechnol­ogy company that has been focused on developing treatments for autoimmune diseases since its launch in 2013. Alexion is a bio-pharmaceut­ical firm focused on developing drugs to treat people with rare diseases.

Ludwig Hantson, Alexion’s chief executive officer, said the deal gives the company an opportunit­y to rebuild its drug pipeline.

“The acquisitio­n of Syntimmune is another critical step in continuing to expand and diversify our portfolio,” Hantson said in a statement released Friday. “We are rapidly advancing the current developmen­t programs and look forward to beginning two pivotal programs next year, including one in warm autoimmune hemolytic anemia.”

Warm autoimmune hemolytic anemia is the most common form of autoimmune hemolytic anemia, according to the National Institutes of Health. It is defined by the presence of autoantibo­dies that attach to and destroy red blood cells at temperatur­es equal to or greater than normal body temperatur­e.

Symptoms of the disease include fatigue, difficulty breathing, jaundice and dark urine. In severe cases of the disease, fever, chest pain, syncope or heart failure may occur, according to the NIH.

The deal to acquire Syntimmune called for an up front payment of $400 million, with the potential for additional payments of up to $800 million iof certain milestone are met.

Alexion officials announced in September 2017 that the company was relocating its headquarte­rs to Boston’s Seaport District and taking 400 jobs with it. The relocation was completed in July and left the company’s former headquarte­rs building at 100 College St. with about 450 workers, many of whom work in research and developmen­t.

 ?? Peter Hvizdak / Hearst Connecticu­t Media file photo ?? The Alexion building at 100 College St. in New Haven.
Peter Hvizdak / Hearst Connecticu­t Media file photo The Alexion building at 100 College St. in New Haven.

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