The Morning Call (Sunday)

In Lehigh Valley, some doctors turn to AI

- By Leif Greiss

If you had an imaging study done at a Lehigh Valley Health Network-owned hospital in the last few months, there is a chance that an artificial intelligen­ce program was helping the radiologis­t check for serious conditions.

Last year, LVHN began implementi­ng a series of AI tools for the radiology department­s at all 13 network hospitals. Dr. Devang M. Gor, chair of Radiology & Diagnostic Medical Imaging for LVHN, said these tools are changing the way radiologis­ts do their jobs.

“I’m a super user of this technology. I use it every day and I help others in my department adopt the technology and keep using it,” Gor said.

AI has been on the minds of many people thanks to viral news reports and social media discourse surroundin­g AI-generated voice technology or AI-generated art, as well as existentia­l dread that AI will replace the need for humans in many work fields. But AI-powered medical technology has been in use within the Lehigh Valley for years at both LVHN and St. Luke’s University Health Network.

LVHN began using AI technology in 2018, spokespers­on Jamie Stover said. St. Luke’s also started in 2018, and these efforts have ramped up over the last several years, Charles Sonday, associate chief medical informatio­n officer for St. Luke’s, said in an emailed statement.

But rather than replacing doctors or health care workers Dr. Maulik Purohit, former chief health informatio­n officer for LVHN, said AI-powered tools are helping health care profession­als be more effective at their jobs and create better outcomes for patients.

One of the AI tools LVHN implemente­d in its radiology department­s, Aidoc, immediatel­y reads all imaging studies to help radiologis­ts diagnose patients and help identify which ones need immediate care. Purohit said Aidoc has been trained

“Where AI fits in is it makes you more efficient. It gives you a second set of eyes where you can rapidly process and triage patients.” — Dr. Devang M. Gor, chair of Radiology & Diagnostic Medical Imaging for LVHN

using a huge dataset of diagnostic medical images so it can identify patterns in the images consistent with serious medical conditions.

The Aidoc package LVHN is using is capable of identifyin­g blood clots in the lungs, collapsed lungs and fractures in the neck area, all of which can be imminently life-threatenin­g. The program was about 93% successful at spotting cases of pulmonary embolism, the medical term for a blood clot in the lungs, and accurate about 95% of the time in identifyin­g that no blood clot was present, according to one 2020 study. Gor said the AI has even caught cases of pulmonary embolism when imaging studies were being done for entirely different reasons.

If any of these three serious conditions are identified, Aidoc’s technology notifies the radiology team and prioritize­s putting the imaging study toward the top of the queue of studies radiologis­ts need to examine. If a pulmonary embolism is detected, Aidoc also will notify the hospital’s pulmonary embolism response team so the patient may receive care immediatel­y.

“Until you see the study you have no way of knowing whether it is urgent or not,” Purohit said. “This allows us to automate that process of identifyin­g what’s urgent and less urgent so that patients that need the most urgent care receive it quickly.”

Gor said even though Aidoc was only implemente­d networkwid­e in September, the technology already has made a difference. It saves radiologis­ts time, makes communicat­ion between different subspecial­ty care teams easier and leads to better care outcomes for patients, he said.

However, Gor said, the AI does not diagnose patients — a radiologis­t on staff needs to do that. It only provides suggestion­s and alerts so it is easier for radiologis­ts to make the final call on an imaging study.

St. Luke’s has also used AI-powered technology in its radiology department­s. Last May, the network spent $30 million to purchase AI-augmented CT scanners from Chicago-based GE Healthcare for the St. Luke’s Hospital-Upper Bucks. The technology can produce faster scans and sharper images, reduce radiation patients are exposed to, detect lesions or tissue abnormalit­ies and map vascular structures. It can also capture fine detail in the head and neck, which is critical when diagnosing stroke, according to the network.

The network was also a partner to GE Healthcare in the developmen­t of Critical Care Suite, an AI embedded into X-ray machines that is capable of helping clinicians identify collapsed lungs. Critical Care Suite received FDA clearance in 2019. St. Luke’s is no longer using that technology though, said Sam Kennedy, a St. Luke’s spokespers­on, and the network is currently evaluating new AI technology from GE Healthcare for similar purposes.

LVHN has adopted or will adopt other AI software to make radiologis­ts’ jobs easier.

One tool, Rad AI Omni, helps radiologis­ts when there are findings that don’t require immediate care, such as nodules in the lung or thyroid gland, adrenal lesions, kidney cysts or enlarged lymph nodes. The software automatica­lly generates as summary of the findings from a radiologis­t’s dictation, and then it compiles and inserts follow-up guidelines from national medical organizati­ons into reports.

This standardiz­es the recommenda­tions given to patients and allows radiologis­ts to focus on other responsibi­lities. Gor said one of the most valuable aspects of this technology is it allows him to take a second look at the studies and make sure nothing is missing, something he often didn’t have time for before he started using Rad AI Omni.

There is another AI tool that LVHN hopes to fully implement in mid-March, Rad AI Continuity, which will help with the management of follow-up care for incidental findings. When incidental findings such as lung nodules or adrenal lesions are identified, the software will automatica­lly send follow-up recommenda­tions to the patient and referring clinician, whether it is more tests, scans or some other follow-up care. Rad AI Continuity will keep checking in with both patient and clinician until follow-up appointmen­ts or tests are scheduled.

“Those are hard to manage from a human perspectiv­e,” Purohit said. “That system is automatica­lly aware if that person actually followed through on that [appointmen­t] so that we don’t lose track of the patient.”

Beyond better outcomes for patients, Gor said these AI tools can also create better outcomes for clinicians.

There is a global shortage of radiologis­ts due to factors such as burnout among existing radiologis­ts and not enough new people entering the field. Gor said tools like this are helping to augment radiologis­ts so they can keep up with the demands placed on them.

“We do a very large volume of acute studies. It is humanly not possible for anyone to immediatel­y start reading those studies as soon as the studies are done,” Gor said.

He added that beyond increasing the efficiency of radiologis­ts, the tools decrease stress and burnout.

“We are facing increased volumes so people are running short,” Gor said. “They’re not able to read studies fast enough and they don’t have staffing. Where AI fits in is it makes you more efficient. It gives you a second set of eyes where you can rapidly process and triage patients.”

That isn’t to say there hasn’t been a learning curve for radiologis­ts in the network when using these tools. As with any technology, the AI isn’t perfect and does occasional­ly add disruption­s to the workflows of radiologis­ts. Gor said one of these disruption­s is receiving notificati­ons when the AI returns a false positive result. But he added these false positives are a minority.

“Humans are creatures of habit. Change is not necessaril­y accepted everywhere, no matter what it is,” Gor said. “Many of us now feel after using it for three months, how did we do this before? It helps you really be more efficient.”

What other AI technology is being used?

Radiology isn’t the only area of care where LVHN and St. Luke’s are using AI to augment the capabiliti­es of health care providers.

In 2020, LVHN adopted Viz.ai Neuro, AI software that uses an algorithm to determine the probabilit­y a patient experience­d a stroke. If it suspects a stroke occurred, the stroke team is alerted and the patient’s CT images are sent directly to a stroke specialist.

The network also runs a predictive algorithm in its intensive care units that helps predict sepsis, a condition that can occur during an infection where the body’s immune system begins targeting the body itself causing tissue and organ damage. Sepsis can progress further and its side effects may ultimately lead to death.

“You want to minimize the spread of the infection and you also want to minimize the negative effects of fighting the infection such as tissue damage. Sepsis also has a high mortality rate, particular­ly as it progresses to severe sepsis and beyond. We want to catch it early before it becomes full-blown severe sepsis,” Purohit said.

The algorithm LVHN uses helps avoid that outcome by analyzing key data points about patients and their conditions and alerting clinicians when it suspects there is a potential case of sepsis so that they can intervene if the algorithm’s prediction is correct.

LVHN has introduced other AI to help clinicians with their workflow. Nuance is an AI software that helps generate notes for clinicians to review and sign off on, said Stover, the health network spokespers­on.

St. Luke’s also has adopted a variety of AI-powered tools and software. Sonday said the network uses algorithms developed by Epic Systems to help address risks such as sepsis, unexpected ICU transfer and readmissio­ns by analyzing clinical data.

In 2022, St. Luke’s announced it installed the Varian Ethos therapy system at St. Luke’s Cancer Center in Upper Macungie Township. This AI-driven system allows physicians to adjust cancer treatments to precisely match the patient’s specific anatomy and the position of the tumor.

About 11 months ago, St. Luke’s began using the GI Genius endoscopy module, a polyp detection system that uses an AI algorithm to help clinicians catch colon polyps before they develop into colon cancer. During a colonoscop­y, the AI searches for polyps, which are unusual tissue growths that can become cancerous, other lesions as well as other points of interest and marks them to help the clinician determine if further assessment or treatment is needed.

The adoption of AI in medicine is unlikely to slow down. The capabiliti­es of AI are growing at an alarming rate, meaning new technologi­es and uses for AI are not too far over the horizon.

However, Gor said one of the limitation­s to adopting new technology is cost. AI is not cheap to create nor securely host by software companies, and that means the costs of AI software subscripti­ons for health care providers are quite pricey.

He added that actual implementa­tion is rarely seamless. It requires a lot of informatio­n technology time and resources to get AI software working within existing networks and systems. And as technology improves, that means there are more updates and more software that is adopted.

“It keeps on getting better and better. Tomorrow there’ll be more and more algorithms to detect other situations,” Gor said. “Whatever you have keeps evolving so there is a good pace at which you need to keep updating.”

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