Allergy issues bring sinus pressure

DEAR DR. ROACH

>> What are your thoughts regarding histamine intolerance when eating high-histamine foods? I am a 65-year-old female who has suffered from sinus problems since my late teens. In my mid-20s, I underwent allergy testing. My results revealed that molds, many pollens and dust were my main culprits. No food reactions were noted.

I underwent six years of allergy injections and was prescribed antihistamines — Seldane, followed by Histmanal, until they were taken off the market. What continues is tremendous pressure in my sinus cavities. It is worse after a meal. The pressure can wear me out.

I recently came across information about histamine intolerance when eating highhistamine foods. So many of my “healthy” foods are on the list! Does diamine oxidase help?

— Anon.

DEAR READER >> Although the term “histamine intolerance” is frequently used, there isn’t evidence that there is a deficiency in one of the enzymes that metabolize histamine, such as DAO. Treatment with this has not been proven effective in people with concerns similar to yours.

Since you received benefit from antihistamines, you should try one of the newer antihistamines such as cetirizine (Zyrtec) or fexofenadine (Allegra, which is very similar to Seldane). From my reading, using one of these along with an H2 antihistamine, such as famotidine (Pepcid), has been helpful to some.

Another approach is Cromolyn, taken as a liquid before eating.

DEAR DR. ROACH >> I have had numbness on the outside of my right thigh for several years. At times, the area would feel like it was on fire, but that has subsided. My doctor ordered an MRI, but doesn’t seem concerned with the fact that this area is numb all the time. I am 62 and in good health. — D.M.

DEAR READER >> Numbness and burning are cardinal symptoms of nerve disease. The fact that it is so localized suggests the compression of a nerve.

It can happen to anyone, but it often happens when a person has changed weight or when pressure’s applied to the area (such as a belt).