The News-Times

Beta blockers treat chest discomfort

- Keith Roach, M.D. Readers may email questions to: ToYourGood­Health@med .cornell.edu or mail questions to 628 Virginia Dr., Orlando, FL 32803.

Dear Dr. Roach: My sister recently had chest pain during exercise and now she is on metoprolol, but the cardiologi­st hasn’t explained to her the reason for the medication. What could she be on the medicine for?

M.D.

Answer: There are many reasons for chest pain. It happens both within the heart and in other parts of the chest, such as the lining of the lungs (the lungs themselves don’t have nerve fibers) and the chest wall, including the ribs, muscles, cartilage and connective tissue.

Metoprolol is a beta blocker. These medicines work by slowing down the heart, reducing how forcefully it squeezes, and by blocking the circulatin­g hormones epinephrin­e and norepineph­rine, also called adrenaline and noradrenal­ine.

Beta blockers are always used, whenever possible, in people with chest discomfort due to blockages in the arteries to the heart.

If the heart needs more blood than it can get due to the blockages, chest discomfort is the main symptom, but there are others. Indigestio­n, arm pain and back or stomach pain may occur, or people may have shortness of breath, or no symptoms at all. This type of heart disease is called coronary artery disease, and is the reason people get heart attacks in almost every case. People with coronary artery disease should also be taking aspirin and a statin drug, unless there are very good reasons not to give them.

There are other possibilit­ies. Hypertroph­ic obstructiv­e cardiomyop­athy is a different type of heart condition, relating to structural changes in the muscle of the heart itself, not the blood vessels supplying the heart. This condition may also cause chest pain or discomfort especially on exercise, and metoprolol is the most common treatment. Other types of heart failure are often treated with beta blockers as well.

The best source of informatio­n is your sister’s cardiologi­st. If possible, it’s ideal to have a family member come to an appointmen­t. A person gets so much informatio­n from their doctor that oftentimes they get a bit overwhelme­d and have a hard time rememberin­g or explaining what the doctor said.

Dear Dr. Roach: Your recent answer to someone’s complaint about no eating after midnight before a surgery brings to mind my upcoming colonoscop­y. In addition to not eating, I am required to take medication that amounts to totally emptying my bowels for a 24-hour period, plus no food prior to my 3:00 p.m. appointmen­t the next day. This seems to be excessive also, especially to a newly diagnosed diabetic as myself.

M.R.

Answer: Most preparatio­n regimens for colonoscop­y allow a person to take clear liquids during most of the preparatio­n phase, so you can take in enough calories that diabetes does not become a problem. Although, you certainly need to talk to the doctor taking care of your diabetes to discuss what to do with any medication­s you might be taking. The colon needs to be completely empty in order for the gastroente­rologist to get a thorough look inside.

Several people wrote in about the “no food after midnight” rule in surgery, mostly commenting that it is necessary to have everyone fasting, even if their procedure is later in the afternoon, in case of the need for emergency rescheduli­ng. I think that for elective procedures, prolonged fasting has more harms than benefits, and a well-organized operating room should not need every patient to be fasting since midnight.

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