Thursday’s NFL Matchup

BUFFALO (8-3) AT NEW ENGLAND (6-5)

KICKOFF: 8:15 p.m. Amazon Prime Video

FANDUEL SPORTSBOOK NFL LINE: Bills by 4½. AGAINST THE SPREAD: Bills 5-6; Patriots 6-4-1.

SERIES RECORD: Patriots lead 77-47-1.

PLAYERS TO WATCH: Bills QB Josh Allen. In his past three starts at New England, he has nine touchdown passes with no interceptions for a 115.3 passer rating . ... Patriots LB Matt Judon. He leads the league with a career-high 13 sacks.

KEY MATCHUP: Allen vs. Patriots pass rush. Allen used both his arm and legs to hurt the Patriots in Buffalo’s two most recent wins. He had three passing TDs and rushed for 64 yards in the second regular-season meeting last season. He followed that up with five passing TDs and 66 rushing yards in the playoff victory. Preventing Allen from getting outside the pocket and extending plays will be the top priority for the Patriots defense.

KEY INJURIES: The Bills will be without top pass rusher Von Miller, who has been ruled out with a knee injury from Buffalo’s 28-25 win over the Detroit Lions on Thanksgiving. LT Dion Dawkins (ankle) sat out the first two practices of the week . ... The availability of Patriots RB Damien Harris (thigh) and OL Isaiah Wynn (foot) are up in the air after they missed practices Monday and Tuesday. Wynn was inactive last week.

STATS AND STUFF: The Bills enter the game in second place in the AFC East behind Miami (8-3), which holds the head-tohead tiebreaker over Buffalo. The Bills are 0-2 against division rivals with losses at Miami and to the New York Jets . ... Buffalo has won at least eight of its first 11 games of a season for the 14th time in franchise history, and third time in four years.