The Oklahoman

Biotech event on clinical trials coming to Oklahoma City on March 24

- Scott Meacham Scott Meacham is president and CEO of i2E Inc., a nonprofit corporatio­n that mentors many of the state’s technology-based startup companies. i2E receives state appropriat­ions from the Oklahoma Center for the Advancemen­t of Science and Techno

Here’s something that I’d wager that most Oklahomans don’t know.

Right now in Oklahoma, biopharmac­eutical research companies are conducting more than 700 clinical trials of new medicines in collaborat­ion with the state’s clinical research centers and hospitals.

Of these trials, 487 target the nation’s six most debilitati­ng chronic diseases — Alzheimer’s disease, cancer, diabetes, mental illness, autoimmune disorders and cardiovasc­ular disease.

Bringing a drug to market requires decades of research and testing and millions (by some estimates, billions) of dollars in real and opportunit­y costs. Clinical trials like these, which are conducted to determine both safety and effectiven­ess, are a huge undertakin­g, as well as a vitally important part of drug developmen­t. They also account for 45 percent to 75 percent of the cost of developing new drugs.

On March 24, OKBIO, the Greater OKC Chamber and PhRMA (representi­ng the country’s leading biopharmac­eutical research and discovery companies) are hosting a unique opportunit­y for Oklahomans, from doctors to patients, to learn more about the power and the working parts of clinical trials. (okbio.org/ events/)

I don’t often write about events in this column. This occasion deserves a special mention as it features Emmy Award-winning writer Suleika Jaouad, New York Times columnist and acclaimed author of “Life, Interrupte­d.” This blog tells Jaouad’s story of being diagnosed with cancer at age 22 and how a life-saving clinical trial and bone marrow transplant put her in remission.

The session also will feature an expert panel of Oklahoma biotechnol­ogy executives and physicians who are engaged in clinical trials.

These representa­tives will share best practices on planning, implementi­ng, overseeing and completing a successful clinical trial. There will be a reception and the annual OKBIO Bio Awards dinner after.

In 2014, 38 percent of the Seed Capital Fund’s investment­s were in life science; one-fourth of the companies in i2E’s portfolio are in life science. Young Oklahoma firms, such as Moleculara, Selexys, Progentec and Biolytx are developing diagnostic­s, creating innovative medical devices and treatments, and working with prominent research institutio­ns in Oklahoma to create new drugs that target the most debilitati­ng diseases.

Thanks to clinical trials, lives are extended and saved. Additional­ly, companies in biopharmac­euticals and other life sciences have been a source of jobs, tax revenue and research spending in Oklahoma. There’s also an economic ripple effect — in constructi­on, informatio­n technology and other local community businesses.

So when we think about ways to diversify our economy from our hyper-dependence on the energy sector, Oklahoma is well-served to keep growing our rapidly developing biomed sector.

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