Vaccinated people can get breakthrough infections
But shots continue to protect people against severe illness
LOS ANGELES – With coronavirus cases spreading rapidly throughout the nation, reports of infections among those who are fully vaccinated for COVID-19 are increasingly drawing attention.
But while these breakthrough cases are sometimes highlighted as a precautionary tale – a signal of the shots’ shortcomings – the reality is the vaccinations remain as consistently effective as ever where it counts: protecting people against severe illness.
That remains true, officials say, even as Los Angeles County health officials shared a seemingly ominous data point Thursday: 20% of newly diagnosed coronavirus cases in June occurred among vaccinated people. Less than two weeks ago, they said over 99% of COVID-19 cases were among the unvaccinated.
At first blush, these numbers may seem to disagree with each other. But a closer look at the data underscores some key findings cited by public health experts, epidemiologists and infectious disease experts in California and by federal officials.
There are two things occurring: More than half of Californians are now fully vaccinated, yet coronavirus transmission has gone up. And while coronavirus case rates are rising in both vaccinated and unvaccinated people, the rates continue to be much worse in unvaccinated people – a trend that’s expected when viral transmission rises.
Why are there cases among vaccinated people increasing?
The following two statements can be true at the same time:
Between Dec. 7 and June 7, the unvaccinated accounted for 99.6% of L.A. County’s coronavirus cases, 98.7% of COVID-19 hospitalizations and 99.8% of deaths.
Out of all coronavirus cases confirmed countywide in June, 20% occurred in residents who were fully vaccinated.
The first sentence speaks to the extraordinary effectiveness of the vaccines. Yes, the period between Dec. 7 and June 7 does cover a time period when vaccine supply was limited. But it also provides a viewpoint into what hospitals are seeing and explains why doctors are so convinced at the effectiveness and importance of the vaccines: Extraordinarily few hospitalizations and deaths have occurred among vaccinated people.
The latter percentage is not so surprising as it might initially seem.
Say, for instance, there were roughly 1,000 coronavirus cases in a month among fully vaccinated people, and there were 4,000 more coronavirus cases among people who were either unvaccinated or partially unvaccinated. In this community, a population of 10 million people was split: Half were vaccinated, and half were not.
One could focus on how 20% of the coronavirus cases occurred among vaccinated people.
But one could also point out that how, for every 100,000 residents, 10 vaccinated people tested positive, and 40 unvaccinated people tested positive. That means unvaccinated people, in this hypothetical example, are four times as likely to test positive for the virus.
Statewide, officials note that while there are instances of vaccinated people becoming infected, the risk remains much more pronounced for the unvaccinated.
From July 7 to 14, the average case rate among unvaccinated Californians was 13 per 100,000, according to the state Department of Public Health. Among those who had been vaccinated, the comparable figure was 2 per 100,000.
Vaccinations provide a high protection but are not 100%
There is overwhelming evidence the COVID-19 vaccinations in use in the United States continue to provide a high degree of protection – although not 100% – against severe illness, hospitalization and death.
Earlier this week, Dr. Anthony Fauci, the U.S. government’s top infectious-diseases expert, cited data showing the Pfizer-BioNTech and Moderna vaccines were 95% and 94% effective, respectively, versus symptomatic COVID-19. And in the United States, the single-shot Johnson & Johnson vaccine has been 72% effective against clinically recognizable disease.
“Infections after vaccination are expected. No vaccine is 100% effective,” he said. “However, even if a vaccine does not completely protect against infection, it usually, if it’s successful, protects against serious disease.”
Nationally, more than 97% of people now hospitalized for COVID-19 have not been vaccinated, according to Dr. Rochelle Walensky, director of the U.S. Centers for Disease Control and Prevention.
“While seat belts don’t prevent every bad thing that can happen during a car accident, they do provide excellent protection – so much so that we all use them routinely,” L.A. County Public Health Director Barbara Ferrer said. “It wouldn’t really make sense to not use a seat belt just because it doesn’t prevent all injuries from car accidents.”
Similarly, she continued, “Rejecting a COVID vaccine because they don’t offer 100% protection really ignores the powerful benefits.”
People with weak immune systems should still take special care to talk to their doctors about additional protective measures they may want to take.
California hasn’t achieved ‘herd immunity’
For all the progress California has made in terms of vaccinations, it’s now clear the state is still short of achieving “herd immunity” – the level at which enough people have been inoculated or have obtained natural immunity to protect the larger population against the virus.
Even the San Francisco Bay Area‘s highest-in-thestate vaccination rates aren’t high enough to insulate the region from increasing case counts.
Most Bay Area health officers have urged everyone to wear masks in indoor public spaces regardless of vaccination status. And health officials in Contra Costa, Santa Clara and San Francisco counties are strongly urging employers to consider requiring their workers to get vaccinated.
Increasing community transmission will mean more positive tests – even among the vaccinated
When coronavirus transmission rises, the immune systems of fully vaccinated people may come under increased pressure. And officials say it’s to be expected that more fully vaccinated people, if they are tested, will be positive for the coronavirus.
Consider a fully vaccinated person who enters a crowded room with many unvaccinated people, but there are only two infected, contagious people there.
“My chances (as a vaccinated person) of getting infected were really, really small,” relatively speaking, Ferrer said.
But say the room is filled with 30 unvaccinated, infected people. In that case, “my chances – even as a fully vaccinated person – have just gone up” of acquiring a coronavirus infection, she continued.
However, officials note unvaccinated people are still far more likely to test positive for the virus than those who have rolled up their sleeves.
In early July, for every 100,000 L.A. County residents, approximately nine who were either unvaccinated or only partially vaccinated tested positive daily for the coronavirus, according to a chart released by the Department of Public Health. That’s far higher than the daily case rate for fully vaccinated people, for which, fewer than two of every 100,000 residents tested positive.
Earlier this year, there were some initial reports out of India suggesting that the coronavirus strain that later became known as the Delta variant was especially worrisome because so many healthcare workers who had been fully vaccinated were nonetheless being infected.
But subsequent analysis later suggested the vaccines continue to be effective. It’s not that the Delta variant was more likely to break through the immunity offered by the vaccines compared with previous strains of the coronavirus. It’s that rising circulation of the virus will predictably cause more vaccinated people to eventually test positive.
When health officials say a vaccine is 90% effective, that means that 10% of the time it’s not effective, Dr. George Rutherford, an epidemiologist at UC San Francisco, said earlier this year. The more people who are exposed to the coronavirus, the higher the number of so-called breakthrough infections.
“It may not have to do with variants as much as it just has to do with the intensity of the exposure,” Rutherford said.
It’s also important to note that in environments where a high percentage of people are vaccinated, cases stay low, as do hospitalizations and deaths.