The Oklahoman

Immunizing more people is preferred over boosters

Wait, scientists say, most people don’t need it

- Naomi Kresge

COVID-19 vaccines work so well that most people don’t yet need a booster, an all-star panel of scientists from around the world said in a review that’s likely to fuel the debate over whether to use them.

Government­s would be better served on immunizing the unvaccinat­ed and to wait for more data on which boosters, and at what doses, would be most effective, the authors, who included two prominent U.S. Food and Drug Administra­tion experts, argued in a medical journal. They based this on real-world observatio­nal studies and data from clinical trials.

COVID-19 vaccines work so well that most people don’t yet need a booster, an all-star panel of scientists from around the world said in a review that’s likely to fuel the debate over whether to use them.

Government­s would be better served to focus on immunizing the unvaccinat­ed and to wait for more data on which boosters, and at what doses, would be most effective, the authors, who included two prominent U.S. Food and Drug Administra­tion experts, argued in the medical journal The Lancet. They based their assessment on a wide range of real-world observatio­nal studies plus data from clinical trials.

“None of the studies has provided credible evidence of substantia­lly declining protection against severe disease,” the authors wrote.

The review comes as most countries with ample vaccine supplies debate whether to allocate doses for booster shots to prop up immunity and potentiall­y help stop the spread of the more infectious delta variant. The U.S. plans to roll out booster shots starting Monday, though the plan still needs sign-off from the FDA and the Centers for Disease Control and Prevention.

Across the observatio­nal studies done so far, vaccinatio­n has been an average of 95% effective against severe disease, including against more infectious variants such as delta, and more than 80% effective at preventing any infection, the review found.

 ?? EMILY ELCONIN/TNS ?? Vaccinatio­n has been an average of 95% effective against severe disease, including against more infectious variants such as delta.
EMILY ELCONIN/TNS Vaccinatio­n has been an average of 95% effective against severe disease, including against more infectious variants such as delta.

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