The Oklahoman

A link between irritable bowel syndrome and gravity? Dr. James prescribes

- Body Work James, a physician-scientist, is vice president of clinical affairs at the Oklahoma Medical Research Foundation. Cohen is a marathoner and OMRF’s senior vice president and general counsel. Submit your health questions to contact@omrf.org.

Adam’s journal

A friend sent me an article suggesting that gravity might be a factor in causing irritable bowel syndrome. Could this really be true? And if so, what does it mean for people affected by this condition?

Irritable bowel syndrome (IBS) is a chronic digestive disorder that affects an estimated 10% of the world’s population. It manifests in a wide variety of symptoms: abdominal pain, bloating, cramping, constipati­on and diarrhea.

Physicians typically arrive at this diagnosis by ruling out other culprits, and the cause of IBS is unknown. However, scientists have pointed to a number of potential culprits, including disordered communicat­ions between the gut and brain, excessive inflammation, and the microbes that populate the intestinal tract.

In a paper published last year in The American Journal of Gastroente­rology, a scientist suggested a sort of grand theory of IBS. He argued that IBS stems from the body’s inability to manage gravity.

He said that as he thought about each possible explanatio­n, from bacteria to nerve signaling, “I realized they might all point back to gravity as a unifying factor.”

While this theory is unsupporte­d by clinical or experiment­al data, an earlier study published in the journal Gut lends a bit of weight to the idea. Specifically, it found that gas transit and evacuation were faster when research volunteers stood up versus when they rested in bed.

If IBS stems from the body’s inability to manage gravity properly, it could also help explain why exercise sometimes yields positive results for those with the condition.

Still, apart from the idea that standing up and moving around might help relieve symptoms, the gut-and-gravity theory doesn’t carry a lot of practical benefit to those living with IBS.

For those with IBS, physicians typically recommend dietary changes first. Often, they’ll have patients eliminate a category of foods known as FODMAPs, a type of carbohydra­te the small intestine absorbs poorly. If this strategy proves unsuccessf­ul, supplement­s and medication­s may follow.

 ?? ?? Irritable bowel syndrome (IBS) is a chronic digestive disorder that affects an estimated 10% of the world’s population. GETTY IMAGES
Irritable bowel syndrome (IBS) is a chronic digestive disorder that affects an estimated 10% of the world’s population. GETTY IMAGES
 ?? Adam Cohen and Dr. Rod McEver Guest columnists ??
Adam Cohen and Dr. Rod McEver Guest columnists
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