The Reporter (Lansdale, PA)

Doctors’ pay for drug talks drops

- BY CHARLES ORNSTEIN, ERIC SAGARA AND RYANN GROCHOWSKI JONES propublica

Some of the nation’s largest pharmaceut­ical companies have slashed payments to health profession­als for promotiona­l speeches amid heightened public scrutiny of such spending, a new ProPublica analysis shows.

Eli Lilly and Co.’s payments to speakers dropped by 55 percent, from $47.9 million in 2011 to $21.6 million in 2012.

Pfizer’s speaking payments fell 62 percent over the same period, from nearly $22 million to $8.3 million.

And Novartis, the largest U.S. drug maker as measured by 2012 sales, spent 40 percent less on speakers that year than it did between October 2010 and September 2011, reducing payments from $24.8 million to $14.8 million.

The sharp declines coincide with increased attention from regulators, academic institutio­ns and the public to pharmaceut­ical company marketing practices. A number of companies have settled federal whistleblo­wer lawsuits in recent years that accused them of im- properly marketing their drugs.

In addition, the Physician Payment Sunshine Act, a part of the 2010 health reform law, will soon require all pharmaceut­ical and medical device companies to publicly report payments to physicians. The first disclosure­s required under the act are expected in September and will cover the period of August to December 2013.

Within the industry, some companies are reevaluati­ng the role of physician speakers in their marketing repertoire. GlaxoSmith­Kline announced in December that it would stop paying doctors to speak on behalf of its drugs. Its speaking tab plummeted from $24 million in 2011 to $9.3 million in 2012.

Not all companies have cut speaker payments: Johnson and Johnson increased such spending by 17 percent from 2011 to 2012; AstraZenec­a’s pay- ments stayed about flat in 2012 after a steep decline the previous year.

ProPublica has been tracking publicly reported payments by drug compa- nies since 2010 as part of its Dollars for Docs project. Users can search for their doctors to see if they have received compensati­on from the 15 companies that make such informatio­n available online. (We’ve just updated our applicatio­n to include payments made through the end of 2012, totaling $2.5 billion. Forest Labs, which only began reporting in 2012, reported speaking payments of $40 million, more than any other company in Dollars for Docs.)

Some companies in the database said their declines have less to do with the Sunshine Act and more to do with the loss of patent protection for key products. Lilly, for example, began facing generic competitio­n to its blockbuste­r antipsycho­tic Zyprexa in late 2011. Its antidepres­sant Cymbalta lost its patent at the end of 2013.

“The value of educationa­l programs tends to be higher when we’re launching a new medicine or we have new clinical data/new indication,” Lilly spokesman J. Scott MacGregor said in an email, adding that the drop in speaking payments also reflects the increased use of web conferenci­ng.

Pfizer’s patent on Lipitor, its top-selling cholestero­l drug, expired in 2011.

“Like any other company, our business practices must adapt to the changing nature of our product portfolio, based in part on products going off patent and new products being introduced into the market,” company spokesman Dean Mastrojohn said in an email.

Novartis’ patent for its breast cancer drug Femara expired in 2011, its hypertensi­on drug Diovan in 2012 and its cancer drug Zometa in 2013. In a statement, Novartis said that speaking payments dropped in 2012, in part, because of a shift from big blockbuste­r drugs that many doctors prescribe toward specialty products prescribed by fewer physicians. Resources were also shifted “to support potential future product launches.”

The industry’s increased emphasis on expensive specialty medication­s for such conditions as multiple sclerosis or Hepatitis C, has been striking, said Aaron Kesselheim, an assistant professor of medicine at Harvard Medical School. A piece in the New England Journal of Medicine last week noted that half of the 139 drugs approved by the Food and Drug Administra­tion since 2009 were for rare diseases and cancers.

“It’s possible the number of physicians they need to support sales of these items is less, leading to lower payments overall,” Kesselheim said.

In some cases, companies maintained or made smaller cuts to other forms of physician compensati­on while pulling back dramatical­ly on speaking payments. Pfizer’s spending on consultant­s dropped 9 percent from 2011 to 2012, far less than its payments to speakers. The company’s spending on research stayed essentiall­y the same.

Lilly increased spending on physician researcher­s by more than 20 percent, while reducing payments to consultant­s by more than twothirds.

Many bioethicis­ts and leaders of major academic medical centers frown upon physicians delivering promotiona­l talks for drug companies, saying they turn doctors into sales representa­tives rather than leaders in re- search and patient care.

Officials with the Pharmaceut­ical Research and Manufactur­ers of America, the industry trade group, dispute this characteri­zation. They said they are working with their member companies to prepare for the Sunshine Act and have created a campaign to promote the value of drug company-doctor collaborat­ions.

“Companies will make their own independen­t decisions about how to engage profession­als,” said Kendra Martello, PhRMA’s deputy vice president of strategic operations.

Scott Liebman, an attorney who advises pharmaceut­ical companies on the Sunshine Act, said it’s too early to know how much the law’s requiremen­ts are affecting company practices, in part because it’s so new. The fact that some companies are cutting back on speaking while preserving their spending on research and consulting suggests that other business forces could be at play, he added.

“It’s very hard to pinpoint exactly why that’s happening,” Liebman said. “I think there’s a lot of potential answers to that. I just don’t know which is the right one.”

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