The Ukiah Daily Journal

New COVID-19 variant spreading rapidly

- By Dr. Eve Glazier Eve Glazier, M.D., MBA, is an internist and associate professor of medicine at UCLA Health.

Dear Doctors: I live in Boston, and the news here seems to be fixated on a brand-new COVID-19 variant. Omicron was all everyone talked about for a long time. Does this mean the new variant we are hearing about is worse? What are we supposed to do to protect ourselves?

Dear Reader: You're referring to XBB.1.5, an offshoot of the omicron variant. Omicron is itself one of the numerous descendant­s of SARS-COV-2, the novel coronaviru­s that launched the COVID-19 pandemic three years ago. The reason you're hearing so much about this new variant, which is being referred to simply as XBB, is that it has become the dominant strain of the novel coronaviru­s in your area.

According to the Centers for Disease Control and Prevention, genetic testing suggests that the majority of new cases of COVID-19 in the northeaste­rn U.S. are now caused by XBB. Nationally, XBB has gone from causing fewer than 2% of COVID-19 cases at the end of 2022 to more than onefourth of all cases at the start of 2023.

As with all viral variants that begin to circulate in great numbers, the success of XBB is due to the presence of certain mutations. In coronaviru­s variants, mutations include changes to the spike proteins on the outer shell. These structural changes make the variants more successful at slipping past the body's existing defenses. This includes evading both naturally acquired immunity and immunity conferred by vaccines and boosters.

While XBB has proven to be more contagious than its predecesso­rs, it does not appear to be more dangerous. At this time, there has not been a spike in either hospitaliz­ations or deaths due to XBB infections. However, this will likely change as the variant continues its geographic spread.

What's particular­ly worrisome is that XBB has arrived at a time when vaccinatio­n rates against COVID-19 have dropped precipitou­sly. Only 15% of those who are eligible have received the newer bivalent vaccine, which was developed with the variants in mind. On top of that, the majority of people in the U.S. have largely stopped taking protective measures, including the use of masks. That, along with indoor living that is necessitat­ed by the cold winter weather, has increased the risk of infection.

And that brings us to your final question, which is how to guard against infection with XBB. The answer is to get back to the basics. It's crucial to stay up to date with coronaviru­s vaccines and boosters, which have proven to be effective in protecting against severe illness. We urge anyone who hasn't yet received the bivalent booster to do so. When spending time in public places, wear a good-quality and well-fitted mask. If you do become sick with COVID-19, see your doctor. Antiviral medication­s can ease symptoms and shorten the duration of illness. The coronaviru­s and its variants are with us for the foreseeabl­e future. It's up to us to remain vigilant and protect ourselves and those around us.

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