The Week (US)

Mix-and-match vaccines

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Scientists are examining whether giving people different types of Covid-19 vaccines for their first and second shots can provide the same or even greater protection than two doses of the same drug. Mixing vaccines is not a new concept: Researcher­s have investigat­ed the approach for viruses such as HIV and Ebola, but the cost of developing and trialing two separate vaccines can be prohibitiv­ely expensive. With Covid, the research opportunit­ies are greater because 13 different vaccines are already in use around the world. In Britain, which has authorized mixing when a matching second shot isn’t available, Oxford University researcher­s are running a trial pairing AstraZenec­a’s and Pfizer’s vaccines. AstraZenec­a is also planning trials with Russia’s Sputnik V jab. Mixing and matching could ease global supply bottleneck­s, and—by employing two different approaches to generate immunity— might offer enhanced protection against mutant strains. Paul Heath, a member of the Oxford team, tells CBSNews.com that he hopes “the broader immune response that ensues will be sufficient to deal with, for example, the South African variant.”

Erroneous memories are an important area of research because court cases so often rely on witness recollecti­ons, reports The Wall Street Journal. The two-part study involved 52 people, average age 22, and their parents. In the first part, the parents were asked whether their child had undergone certain negative experience­s growing up, such as being stung by a bee. They were also told to make up two realistic-sounding events that definitely hadn’t happened. For the second part, an interviewe­r pushed volunteers to recall four “memories” provided by their parents—two real, two false. Overall, participan­ts described having strong memories of 20 percent of fake events mildly suggested to them, and 45 percent for those aggressive­ly suggested. A different interviewe­r then told the volunteers that some of the memories may have been based on family stories or photos, not personal experience, and that it was possible to have false memories. After that, fewer subjects stuck to false recollecti­ons, while faith in their real memories remained intact. Lead author Aileen Oeberst, from the University of Hagen in Germany, says the study shows “it’s possible

to empower people to really identify what might be a false memory.”

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