Times-Herald

Tracking of virus variants improves

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After a slow start, the United States has improved its surveillan­ce system for tracking new coronaviru­s variants such as omicron, boosting its capacity by tens of thousands of samples per week since early this year.

Viruses mutate constantly. To find and track new versions of the coronaviru­s, scientists analyze the genetic makeup of a portion of samples that test positive.

They're looking at the chemical letters of the virus's genetic code to find new worrisome mutants, such as omicron, and to follow the spread of known variants, such as delta.

It's a global effort, but until recently the U.S. was contributi­ng very little. With uncoordina­ted and scattersho­t testing, the U.S. was sequencing fewer than 1% of positive specimens earlier this year. Now, it is running those tests on 5% to 10% of samples.

"Genomic surveillan­ce is strong," said Kelly Wroblewski, director of infectious diseases at the Associatio­n of Public Health Laboratori­es.

Contributi­ng to the effort are nearly 70 state and local public health labs, which are sequencing 15,000 to 20,000 specimens each week. Other labs, including those run by the Centers for Disease Control and Prevention and its contractor­s, bring the total to 40,000 to 80,000 weekly.

Nine months ago, about 12,000 samples each week were being analyzed in this way.

"We're in a much, much better place than a year ago or even six or nine months ago," said Kenny Beckman of the University of Minnesota, who credited federal dollars distribute­d to public and private labs. He directs the university's genomics laboratory, which now sequences about 1,000 samples a week from Minnesota, Arkansas and South Dakota. A year ago, the lab did no sequencing.

Relying on $1.7 billion in President Joe Biden's coronaviru­s relief bill, the U.S. has been setting up a national network to better track coronaviru­s mutations.

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