Times Standard (Eureka)

Gastropare­sis is treated primarily with diet

- By Dr. Eve Glazier Eve Glazier, M.D., MBA, is an internist and associate professor of medicine at UCLA Health.

Dear Doctor: My husband started having a lot of stomach pain and was also feeling queasy. Needless to say, I feared the worst — cancer — but, instead, his doctor says it’s gastropare­sis. Is it dangerous? What’s the best treatment?

Dear Reader: Gastropare­sis is the name of a condition in which the stomach is slow to empty its contents into the small intestine. This isn’t due to any type of blockage. Instead, the cause is a malfunctio­n in the nerves that serve the region. This includes the vagus nerve, which animates the stomach muscles and helps send food to the small intestine. Symptoms include the pain and nausea your husband experience­d, as well as poor appetite, feeling full after only small amounts of food or drink, heartburn and unintended weight loss.

When functionin­g properly, the stomach takes about four hours to saturate its contents with gastric juices, break everything up into smaller particles and pass the majority of it along to the small intestine. For people living with gastropare­sis, the process takes significan­tly longer. The result is delayed digestion, which can lead to a range of problems. Food that remains in the stomach for too long is susceptibl­e to fermentati­on, which can encourage the growth of bacteria. The condition can interfere with appetite and sometimes leads to malnutriti­on. When the contents of the stomach are stalled, they can coagulate into a mass known as a bezoar, which can cause a blockage. And for people living with diabetes, the delayed movement of food from the stomach to the small intestine can interfere with glucose control.

Gastropare­sis is often seen in people living with diabetes, which can cause nerve damage. It may also arise as the result of viral stomach infections, hypothyroi­dism, certain autoimmune or neurologic­al disorders, or surgical injury. It’s a known (albeit rare) side effect of medication­s such as opioids, antihistam­ines, tricyclic antidepres­sants and calcium-channel blockers, which can impede digestion.

Diet is important in the management of gastropare­sis, with an emphasis on nutrient density and ease of digestion. Patients are asked to eat small meals of soft, wellcooked food, and to avoid high-fat foods, which delay the emptying of the stomach. Foods high in fiber are difficult to digest and are also limited, or in some cases eliminated. Fruits and vegetables, which contain nondigesti­ble fiber, should be served cooked, and in some cases pureed. For instance, instead of an apple, a patient will have a small serving of applesauce. They are also encouraged drink liquids that contain glucose and electrolyt­es, including clear soups, low-fat broths, low-fiber fruit and vegetable juices, or sports drinks. Since glucose control and malnutriti­on are both a challenge, many people with gastropare­sis work with a registered dietitian.

When the condition can’t be managed with diet, medication­s that cause the stomach to contract and emerging therapies such as electrical gastric stimulatio­n may be an option. In severe cases, surgery may be necessary. We recommend that your husband seek out a gastroente­rologist to fully assess his case and plan his treatment.

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