49ers (1-4) at Packers (2-2-1)

Monday, 8:15 p.m. ET, Lambeau Field, Green Bay, Wisconsin

TV: ESPN

Danny Sheridan’s line: by 9

49ers’ keys to victory: Control the ball on offense and pressure Aaron Rodgers. The 49ers need to stay balanced and protect QB C.J. Beathard, using rookie RB Matt Breida as the focal point of the offense. Beating Rodgers at Lambeau Field is never easy, but the best way to combat the two-time MVP is getting an effective pass rush with the front four. DL DeForest Buckner, Arik Armstead and Solomon Thomas must be consistently disruptive or Rodgers will pick the 49ers apart.

Packers’ keys to victory: Attack the 49ers’ biggest weakness and stop the run. Opposing quarterbacks have sliced and diced San Francisco’s secondary this season, providing an opportunity for a big night from QB Aaron Rodgers. He is getting healthier every week, and the Packers could return WRs Randall Cobb and Geronimo Allison. The defense must contain the 49ers’ high-efficiency run game and force QB C.J. Beathard to move the football through the air. The Packers will like their odds if the game comes down to Rodgers vs. Beathard.

Matchup to watch: 49ers TE George Kittle vs. Packers LB Oren Burks. Kittle has been the 49ers’ best offensive weapon through five games. The Packers likely will counter with Burks, a rookie with coverage ability and a growing role.

Who wins? The 49ers haven’t been an easy out in 2018, but it’s difficult to envision Beathard walking into Lambeau Field and beating Rodgers in a prime-time matchup.

Packers, 28-20 Packers