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Scientist sentenced for gene-editing babies

- Contributi­ng: Shanshan Wang and Yu Bing

BEIJING – A Chinese scientist who set off an ethical debate with claims that he had made the world’s first geneticall­y edited babies was sentenced Monday to three years in prison because of his research, state media said.

He Jiankui, who was convicted of practicing medicine without a license, was fined 3 million yuan ($430,000) by a court in the southern Chinese city of Shenzhen, China’s official Xinhua News Agency said.

Two other researcher­s involved in the project received lesser sentences and fines. Zhang Renli was sentenced to two years in prison and fined 1 million yuan. Qin Jinzhou received an 18-month sentence, though he got a two-year reprieve, and a 500,000-yuan fine.

He, the lead researcher, shocked the scientific world when he announced in November 2018 that he had altered the embryos of twin girls who had been born that month. He described his work to The Associated Press.

The announceme­nt sparked a global debate over the ethics of gene editing. He said he used a tool called CRISPR to try to disable a gene that allows the AIDS virus to enter a cell, in a bid to give the girls the ability to resist the infection. The identity of the girls has not been released, and it isn’t clear whether the experiment succeeded.

The CRISPR tool has been tested elsewhere in adults to treat diseases, but many in the scientific community denounced He’s work as medically unnecessar­y and unethical, because any genetic changes could be passed down to future generation­s. The United States forbids editing embryos except for lab research.

He told the AP in 2018 that he felt a strong responsibi­lity to make an example and that society would decide whether to allow the practice to go forward. He disappeare­d from public view shortly after he announced his research at a conference in Hong Kong 13 months ago.

The Xinhua report, citing the court’s verdict, said the researcher­s were involved in the births of three gene-edited babies to two women, confirming reports of a third baby.

The court said the three researcher­s had not obtained qualificat­ion as doctors to practice medicine, pursued fame and profits, deliberate­ly violated Chinese regulation­s on scientific research and crossed an ethical line in scientific research and medicine. The court said they fabricated ethical review documents.

He studied in the USA before setting up a lab at the Southern University of Science and Technology of China in Shenzhen. The verdict accused him of colluding with Zhang and Qin, who worked at medical institutes in the same province.

 ?? MARK SCHIEFELBE­IN/AP ?? He Jiankui, shown in October in a lab in Shenzhen, China, claims he helped make world's first geneticall­y edited babies.
MARK SCHIEFELBE­IN/AP He Jiankui, shown in October in a lab in Shenzhen, China, claims he helped make world's first geneticall­y edited babies.

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