What is the cor­pus cal­lo­sum?

Wellness Update - - CLEVLAND CLINIC -

The cor­pus cal­lo­sum is the largest mid­line struc­ture of the brain. • It be­gins to de­velop around the 10th

to 11th week of preg­nancy • Con­sists of over 200 mil­lion nerve fibers that

con­nect the two hemi­spheres of the brain • Trans­fers and in­te­grates mo­tor, sen­sory, and cog­ni­tive

in­for­ma­tion be­tween the cere­bral hemi­spheres • Con­tin­ues to ma­ture through­out preg­nancy

and into childhood and ado­les­cence The type of cal­losal ab­nor­mal­ity that de­vel­ops de­pends on the cause and tim­ing of the dis­rup­tion to pre­na­tal brain de­vel­op­ment. If the cor­pus cal­lo­sum does not form dur­ing the pre­na­tal pe­riod, it will not de­velop later. Those with ACC can be af­fected in a range that runs from seem­ingly nor­mal to se­ri­ously hand­i­capped. The only way to de­tect ACC is through an MRI. There is no cure and the af­fects are per­ma­nent. As the af­fected in­di­vid­ual grows, the dis­or­der doesn’t get worse—but then, it doesn’t get bet­ter. Be­cause it is a birth dis­or­der, in­fants with ob­vi­ous signs and symp­toms such as lack of mo­tor skill de­vel­op­ment, walk­ing, talk­ing, etc., are most likely to be di­ag­nosed. It’s those with less se­vere symp­toms who are usu­ally di­ag­nosed later in life— or not at

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