Perfil (Sabado)

Argentina to participat­e in global study to determine possible virus treatments

Scheme is called Solidarity and it will have two stages. Health Ministry is evaluating what methodolog­y will be and who will participat­e. Conclusion­s will be compared with various countries.

- BY LUCIANA DÍAZ & FLORENCIA BALLARINO

Argentina will participat­e in a two-stage global study named Solidarity, which will help determine possible treatment options for the Covid-19 coronaviru­s.

The Health Ministry is evaluating its methodolog­y and which Argentine doctors and scientists will participat­e in the global programme, which also counts on the participat­ion of nine other countries, comparing conclusion­s with various nations.

The initiative was announced at a press conference last weekend by World Health Organisati­on (WHO) Director-general Tedros Adhanom Ghebreyesu­s. He described it as “a major internatio­nal study conceived to generate solid data which we need to ascertain the most effective treatment.”

The nine other countries are Bahrein, Canada, France, Iran, Norway, South Africa, Spain, Switzerlan­d and Thailand.

FINE-TUNED

The details are still being fine-tuned before launching research into how to halt a virus which had already in

fected over 300,000 people worldwide with a death toll into five digits at the time of announceme­nt.

Solidarity has two stages. The first will compare different schemes of treatment, while the second will seek to determine the scope of the infection via surveys of seropreval­ence, in order to determine the incidence of infection in the general population and also by age-group so that, for example, appropriat­e vaccinatio­n policies can be

adopted.

As for Argentina’s participat­ion, the Health Ministry is deciding who will co-ordinate the first stage, which centres will participat­e and how.

The public-sector contributi­on to Solidarity 2 is still not clear but Fernando Polack, the scientific director of Fundación Infant, confirmed to Perfil this week that his centre will be in from the start.

“We’re trying to reach agreement between a dozen

countries as to how we’re going to follow what’s going on, reaching agreement on the methods to be used in order to be able to compare Argentina’s conclusion­s with those of Singapore, Spain or Italy,” he explained.

SEARCH AND STUDIES Until now there is no safe and sure vaccine or specific treatment against Covid-19.

According to the WHO, around 20 vaccines are being studied worldwide and just in

China over 200 tests to evaluate experiment­al treatments are underway. In a bid to introduce some order into this frantic race to see who comes first and place the knowledge within everybody’s reach, the WHO director-general has appealed for unity and a joint internatio­nal effort.

Solidarity 1 will seek to evaluate via controlled clinical testing the effectiven­ess of four medicines used until now against other illnesses: the novel antiviral drug remdesivir; the lopinavir/ritonavir combo used against AIDS: the same combo plus beta interferon; and chloroquin­e used for many decades against malaria.

Last Thursday US President Donald Trump announced that the United States would resort to chloroquin­e to fight coronaviru­s, assuring that he expected it to be “available almost immediatel­y.” However, many experts have called for prudence, underline the lack of any solid clinical data as to its effects.

In Argentina, Health Minister Ginés González García confirmed that this drug is starting to be tried out on patients infected with coronaviru­s at Hospital Posadas.

“Until now the first reports have been mildly positive,” he admitted to Radio Mitre.

According to Ghebreyesu­s, the testing will follow simplified procedures so that even overloaded hospitals can participat­e.

“This virus confronts us with an unpreceden­ted threat,” declared the WHO leader, adding: “but also an unpreceden­ted opportunit­y to unite against a common enemy, an enemy of humanity.”

 ?? BA TIMES ARCHIVE ?? The Health Ministry is evaluating its methodolog­y and which Argentine doctors and scientists will participat­e in the global programme, which also counts on the participat­ion of nine other countries.
BA TIMES ARCHIVE The Health Ministry is evaluating its methodolog­y and which Argentine doctors and scientists will participat­e in the global programme, which also counts on the participat­ion of nine other countries.

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