Get the tone
I’m keeping to a typical rock tone for this series. I use a Fender Strat, so I always use a distortion pedal to boost the signal before it gets to the amp. Generally, try to go for 25% of your distortion from the pedal and 75% from the amp. You’ll find that the results are sweeter, more even and tight sounding than when getting 100% of the distortion from the amp. Typically, most amplifiers should be set as above. Some delay added to the guitar track, in tempo with the track, will help to give both size and smoothness to the guitar sound.