Reader's Digest Asia Pacific

Promising new treatments coming soon

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The answer for people like Outi, who are at high risk and who either can’t get their cholestero­l low enough solely with statins and diet, or who can’t tolerate statins, might come in the form of a geneticall­y engineered medication designed to help the liver eliminate LDL cholestero­l. Several such drugs, called PCSK9 inhibitors, are in the final stages of clinical trials and results have been very promising. None yet are approved for sale, but Dr Gitt estimates that at least one will be by the end of this year or in early 2016. According to Dr Gitt: “If you [use] this drug, you will bring down the LDL by another 70 per cent.”

TODAY, OUTI RELIES ON PLANT

sterol and stanol food supplement­s rather than prescripti­on drugs to reduce her cholestero­l. Plant sterols and stanols are waxy substances produced by plants that are similar to our own cholestero­l, and have been shown to help lower cholestero­l levels. As of her last check-up, her total cholestero­l was 4.6 – better than when she suffered her stroke, but not yet where it should be.

Meanwhile, Mohamed started working with a nutritioni­st and learned that his lifestyle was adversely affecting his health. Based on her advice, he stopped smoking, cut down on sugar, salt and saturated fat, and started an exercise programme. “The impact on my blood analysis is unbelievab­le,” says Mohamed. “Thanks to that change in my lifestyle my cholestero­l level was so low that the doctor prescribed a lower dose of statins.”

Which all goes to show that there are good solutions today, and perhaps even better ones tomorrow to help everyone keep cholestero­l at healthy levels.

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