Mice Cured of Metabolic Disorder

American scientists use CRISPR to cure mice of tyrosine metabolism disorder, which can also cause liver failure in humans. The disease results from a mutation in the Fah gene. By injecting the CRISPR tools into mice liver cells, scientists manage to correct the mutation.

DNA template 4 The cell tries to repair the gene, using the injected DNA template as its working drawing. So, the required change is introduced into the gene. Guide RNA

PATRICE LATRON/SCIENCE PHOTO LIBRARY CRISPR corrects sick gene in young mice.