Science Illustrated

Artificial Skin Saves Boy's Life

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MEDICINE Eighty per cent of Hassan's skin had fallen of his body, which looked like one large open wound caused by fire. Over time, the condition – caused by a rare genetic disease known as epidermoly­sis bullosa – would kill him due to secondary infection.

A new method was used to save Hassan’s life. First, scientists extracted stem cells from a bit of the boy’s remaining skin. A virus equipped with a healthy version of the LAMB3 gene, which was defective in the boy, was subsequent­ly injected into the stem cells. The geneticall­y modified cells were propagated in a lab, and new, healthy skin was produced. The scientists repeated the process, until they had made and supplied Hassan with about 1 m2 of skin.

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 ??  ?? 7-year-old Hassan has new, geneticall­y modified skin on almost all of his body.
7-year-old Hassan has new, geneticall­y modified skin on almost all of his body.

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