The Phnom Penh Post

Are your sperm in trouble?

- Nicholas Kristof

LET’S begin with sex.

As a couple finishes its business, millions of sperm begin theirs: rushing towards an egg to fertilise it. But these days, scientists say, an increasing proportion of sperm – now about 90 percent in a typical young man – are misshapen, sometimes with two heads or two tails.

Even when properly shaped, some sperm are pathetic swimmers, veering like drunks or paddling in circles. Sperm counts also appear to have fallen sharply in the last 75 years.

“There’s been a decrease not only in sperm numbers, but also in their quality and swimming capacity, their ability to deliver the goods,” said Shanna Swan, an epidemiolo­gist at the Icahn School of Medicine at Mount Sinai, who notes that researcher­s have also linked semen problems to shorter life expectancy.

This is an urgent concern that affects our species’ future. Studies suggest a culprit is a common class of chemicals called endocrine disruptors, found in plastics, cosmetics, couches, pesticides and other items. The environmen­tal links and studies over 25 years add to the concern that the world’s sperm are in trouble.

And so are men and boys. Apparently related to the problem of declining semen quality is an increase in testic- ular cancer in many countries, in undescende­d testicles, and in a congenital malformati­on of the penis called hypospadia­s (in which the urethra exits the side or base of the penis instead of the tip). These problems are often found together and are labelled testicular dysgenesis syndrome. There is still disagreeme­nt about the scale of the prob- lem, and the data aren’t always reliable. But some scientists are beginning to ask: At some point, will we face a crisis in human reproducti­on? Might we do to ourselves what we did to bald eagles in the 1950s and 1960s?

“I think we are at a turning point,” Niels Erik Skakkebaek, a Danish fertility scholar and pioneer in this field, told me. “It is a matter of whether we can sustain ourselves.”

One recent study found that of sperm donor applicants in Hunan province, China, 56 per- cent qualified in 2001 because their sperm met standards of healthines­s. By 2015, only 18 percent qualified.

“The semen quality among young Chinese men has declined over a period of 15 years,” concluded the study, involving roughly 30,000 men.

Perhaps even more alarming, Canadian scientists conducted a seven-year experiment on a lake in Ontario, adding endocrine disrupting chemicals and then observing the impact on fathead minnows. The chemicals had a devastatin­g impact on males, often turning them into intersex fish, with characteri­stics of both sexes incapable of reproducin­g.

The crisis for male reproducti­ve health seems to begin in utero. Male and female fetuses start pretty much the same, and then hormones drive differenti­ation of the sexes. The problem seems to be that endocrine disrupting chemicals mimic hormones and confuse this process, interferin­g with the biological process of becoming male.

How should we protect ourselves? Swan said she avoids plastics as much as possible, including food or drinks that have touched plastic or been heated in plastic. She recommends eating organic to avoid pesticide residues, and avoiding Tylenol and other painkiller­s during pregnancy. Receipts from thermal printers, like at petrol pumps and ATMs, are also suspect. When in doubt, she consults guides at ewg.org/consumer-guides.

Yet this isn’t just a matter of individual action, but is also a public policy issue that affects tens of millions of people, their capacity to reproduce.

What’s needed above all is more aggressive regulation of endocrine disrupting chemicals. The United States has been much slower than Europe to regulate toxic chemicals, and most chemicals sold in the US have never been tested for safety.

The larger question is why we allow the chemical industry – by spending $100,000 on lobbying per member of Congress – to buy its way out of effective regulation of endocrine disruptors. The industry’s deceit marks a replay of Big Tobacco’s battle against regulation of smoking.

If you doubt the stakes, remember this: Our human future will only be as healthy as our sperm.

 ?? LIZA DONNELLY/THE NEW YORK TIMES ??
LIZA DONNELLY/THE NEW YORK TIMES

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