Calgary Herald

THE CORONAVIRU­S THAT HAS INFECTED MORE THAN 11 MILLION PEOPLE WORLDWIDE MAY HAVE BEEN HERE ALL ALONG WAITING TO BE ‘IGNITED’ RATHER THAN STARTING IN CHINA, AN OXFORD UNIVERSITY EXPERT BELIEVES.

- SARAH KNAPTON

Coronaviru­s may have lain dormant across the world and emerged when environmen­tal conditions were right for it to thrive — rather than starting in China, an Oxford University expert believes.

Dr. Tom Jefferson, senior associate tutor at the Centre for Evidence-based Medicine (CEBM) at Oxford, and visiting professor at Newcastle University, says there is growing evidence the virus was elsewhere before it emerged in Asia.

Last week, Spanish virologist­s announced they had found traces of COVID-19 in samples of waste water collected in March 2019, nine months before the disease was seen in China. Italian scientists have also found evidence of the virus in sewage samples in Milan and Turin, from mid-december, many weeks before the first case was detected, while experts have found traces in Brazil from November.

Jefferson believes that many viruses lie dormant and emerge when conditions are favourable. It also means they can vanish as quickly as they arrive.

“Where did SARS-1 go? It’s just disappeare­d,” he said. “So we have to think about these things. We need to start researchin­g the ecology of the virus, understand­ing how it originates and mutates. We may be seeing a dormant virus that has been activated by environmen­tal conditions. There was a case in the Falkland Islands in early February. Now, where did that come from?

“There was a cruise ship that went from South Georgia to Buenos Aires and the passengers were screened and then on day eight ... they got the first case. Was it in prepared food that was defrosted and activated?

“Strange things like this happened with Spanish Flu. In 1918, around 30 per cent of the population of Western Samoa died of Spanish Flu and they hadn’t had any communicat­ion with the outside world.

“The explanatio­n could only be that these agents don’t come or go anywhere. They are always here and something ignites them, maybe human density or environmen­tal conditions, and this is what we should look for.”

Jefferson believes that the virus may be transmitte­d through the sewerage system or shared bathroom facilities, not just through droplets expelled by talking, coughing and sneezing.

Jefferson and Prof. Carl Heneghan, director of the CEBM, have called for an investigat­ion similar to that carried out by John Snow in 1854, which showed cholera was spreading in London from an infected well in Soho.

Exploring why so many outbreaks happen at food factories and meat-packing plants could uncover major new transmissi­on routes, they believe. It may be shared bathroom facilities coupled with cool conditions that allow the virus to thrive.

“We’re doing a living review, extracting environmen­tal conditions, the ecology of these viruses which has been grossly understudy,” said Jefferson.

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