Journal Pioneer

Weeding out serotonin disruptors

- Drs. Oz and Roizen Mehmet Oz, M.D. is host of “The Dr. Oz Show,” and Mike Roizen, M.D. is Chief Wellness Officer and Chair of Wellness Institute at Cleveland Clinic. To live your healthiest, tune into “The Dr. Oz Show” or visit www.sharecare.com.

“I ain’t left this little room ... tryna concentrat­e to breathe, cause this piff [weed] so potent, killing serotonin,” sings Grammy-winning R&B singer The Weeknd in his song “Initiation.”

With over 4 million views on YouTube, it seems the moodenhanc­ing neurotrans­mitter and all-around gut-loving hormone serotonin has made its way into mainstream pop culture! The Weeknd is probably right; research shows that chemicals in marijuana lower serotonin levels.

The repercussi­ons are far more serious than the munchies.

For a new study, Johns Hopkins researcher­s reviewed brain scans of over 50 people, and found that those with mild cognitive decline had lower levels of serotonin compared with people with healthy brains. Maybe protecting serotonin levels (bye-bye, weed) will help you avoid progressio­n to Alzheimer’s disease. Another lab study found that a lack of neurons that modulate serotonin can lead to a buildup of amyloid plaques in the brain — one of the hallmarks of Alzheimer’s. Decreased respirator­y and cardio health (caused by smoking anything) may contribute to decline of healthy neurons.

While scientists untangle the link between Alzheimer’s and low serotonin, you want to make sure enough of this chemical is circulatin­g in your brain and gut. Serotonin modulates a whole host of things, from mood and appetite to sleep and sexual function. Boost your supply by:

– Shooting for at least 30 minutes exercise daily (more is better).

– Catching some rays. Exposure to bright light of any kind can boost serotonin levels. – Eating foods with tryptophan (turkey, nuts, pumpkin seeds and salmon).

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