Journal Pioneer

Are your medication­s triggering depression?

- Drs. Oz and Roizen Mehmet Oz, M.D. is host of “The Dr. Oz Show,” and Mike Roizen, M.D. is Chief Wellness Officer and Chair of Wellness Institute at Cleveland Clinic. To live your healthiest, tune into “The Dr. Oz Show” or visit www. sharecare.com.

When Richard Farina wrote “Been Down So Long It Looks Like Up To Me” in 1966, he knew the Beat and Hippie subculture­s from the inside out – and felt the world was so topsy-turvy that feeling down was a kind of new normal, fueled in part by drugs. Finding that depression is a new normal because of common drugs they take is something an astounding 37 per cent of American adults can relate to, according to a study published in JAMA. Researcher­s looked at the medication use of more than 26,000 adults from 2005 to 2014. Turns out, 203 often-used prescripti­on drugs, some of which are also available over-thecounter, have depression and/or suicide listed as side effects. The meds included proton pump inhibitors and antacids, as well as sedatives, anti-seizure meds, hormonal contracept­ion, blood pressure and heart medication­s, and painkiller­s.

The research also showed that if you’re taking more than one of these, your risk of depression increases.

Around 15 per cent of adults who use three or more, which is not uncommon, experience depression, compared with 5 per cent of folks taking none, and 7 per cent of those taking just one. Drugs listing suicide as a potential side effect showed similar results.

So if you’re feeling fatigued, sleeping too much or not enough, are sad or disengaged, or think about suicide, talk to your doctor about the prescripti­on and over-the-counter meds you’re taking.

You may want to explore alternativ­es, including lifestyle changes that could ease pain and digestive woes and lower blood pressure, or opt for nonhormona­l contracept­ion.

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