National Post

Red wine can ward off cavities, study suggests

- Sharon Kirkey

No one is suggesting people start rinsing with Merlot after every meal, but a new study suggests compounds in red wine might help ward off cavities and gum disease.

A study published Wednesday f ound two polyphenol­s in red wine — natural compounds that have antioxidan­t effects — that seem to help prevent common plaque-causing bacteria from forming sticky films on teeth and gums.

It’s not clear how, exactly, the polyphenol­s reduce the stickiness of bacteria that globs onto gum tissue, and others cautioned the doses used in the experiment­s were in far higher concentrat­ions than occurs naturally in wine.

But cavities, gum disease and tooth loss affect 60 to 90 per cent of the global population. “Traditiona­l therapies used for the maintenanc­e of oral health present some limitation­s, and the search of natural-origin therapies is gaining attention,” the Spanish team reported in the Journal of Agricultur­al and Food Chemistry.

Cavities and other dental diseases start when bacteria in the mouth form sticky biofilms — colonies of bacteria difficult to kill. The bacteria form plaque and produce acid that can ultimately erode the surface of a tooth.

Four years ago, the same team grew cultures of cavitycaus­ing bacteria in the lab, and then dipped the biofilms in different liquids. Red wine — with or without alcohol — as well as red wine spiked with grape seed extract were the most effective at getting rid of the bacteria.

The new study goes further. Working with cells that mimicked gum tissue, the researcher­s found two specific red wine polyphenol­s — caffeic and p- Coumaric acid — were better than total wine extracts at preventing porphyromo­nas gingivalis and other bacteria from sticking to gums.

The effects were stronger when combined with a probiotic, so- called “friendly” bacteria thought to keep the gut healthy.

The exact mechanism isn’t known but the researcher­s think that metabolite­s that form when we start digesting polyphenol­s in our mouths might play a role.

The findings might inspire new treatments, they said. “Mouthwashe­s and chewing gums have been proposed as interestin­g matrices for the applicatio­n of dietary polyphenol­s in the management of oral health,” lead author Dr. Victoria Moreno-Arribas, from the Spanish National Research Council in Madrid, told the Daily Mail.

IF YOU REMOVE THAT STICKY LAYER NOTHING ELSE ADHERES.

“It’s wonderful, important work,” said Dr. Larry Levin, president of the Canadian Dental Associatio­n.

“Pretty well every university involved in oral health research is looking at ways to interrupt the process by which plaque adheres and causes dental damage,” he said.

Still, a test- tube study “is miles from being a product that can be helpful in the real world,” Levin cautioned. “But that’s how scientific breakthrou­ghs are made.”

Scientists are searching for ways to keep bacteria from adhering to teeth or render it incapable of causing disease. “The ultimate goal would be to have a rinse or toothpaste or some other dental product that would do both,” said Levin.

Brushing and flossing at least once a day is still the gold standard. “If you remove that sticky layer nothing else adheres,” Levin said. A new mat forms every day.

The new study doesn’t mean swishing red wine would have any noticeable effect, he added. “And you still have the alcohol content and other things in wine. I don’t think we know what the longterm effects would be.”

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