National Post

‘Moral hazard’ of saving an addict’s life

JURISDICTI­ONS HAVE ACTED TO INCREASE ACCESS TO NALOXONE.

- Me Mc Ar gan dle The Washington Post

In the 1960s, after some prodding from Ralph Nader, American government regulators began a major push for safer cars. Which made University of Chicago economist Sam Peltzman wonder just how much safer these innovation­s made us. Specifical­ly, he wondered about what economists call “moral hazard” — our tendency to take more risks when we’re insulated from the costs of that risk-taking.

In 1975, Peltzman published an article innocuousl­y titled “The Effects of Automobile Safety Regulation.” His conclusion, however, was explosive: “Data imply some saving of auto occupants’ lives at the expense of more pedestrian deaths and more nonfatal accidents.” Less fearful of accidents, drivers were piloting their vehicles more recklessly, substantia­lly reducing the life- saving benefits of the regulation. Economist Gordon Tullock suggested that if regulators really wanted people to drive more safely, they’d require automakers to mount a spike in the middle of each steering wheel, pointed toward the driver’s breast.

The “Peltzman Effect” doesn’t mean, however, that auto safety is useless. Drivers may be a little more reckless, but there’s been a steady decline in deaths per 100 million miles of driving. In 1965, that number stood at 5.3. It is now 1.2.

But it seems there may be one area where the Peltzman Effect not only exists, but is large enough to completely erase the benefits of a safety measure: opiate use. A chemical called naloxone acts as an “opioid antagonist” — which is to say, it reverses the drug’s effects on the body. It can thus save people who have overdosed.

As opioid usage has worsened in t he United States, more and more jurisdicti­ons have acted to increase access to naloxone. Not only first responders but also friends, family and even librarians have started to administer it. These state laws were passed at different times, giving researcher­s Jennifer Doleac and Anita Mukherjee sort of a natural experiment: They could look at what happened to overdoses in areas that liberalize­d naloxone access and compare the trends there to places that hadn’t changed their laws.

Their results are grim, to say the least: “We find that broadening Naloxone access led to more opioid- related emergency room visits and more opioid- related theft, with no reduction in related mortality.”

You can never assume that the results of one study, however well done, are correct. But these results look pretty robust. If they hold up, they would mean that naloxone is not saving lives; all we’re doing is spending a lot of money on naloxone to generate some increase in crime.

It makes a certain amount of sense that the Peltzman Effect would show up particular­ly strongly in drug users; after all, drugs hijack the brain’s reward system, redirectin­g it toward drugseekin­g even at high personal risk. Drug users, one would think, would be highly likely to recalibrat­e their risk- taking so that the risk of death remains constant, while the frequency and potency of drug use increases.

The coldly l ogical response to this would seem to be to discontinu­e naloxone use. But there’s something repulsive about that conclusion, and Doleac and Mukherjee can’t bring themselves to go there. “Our findings do not necessaril­y imply that we should stop making Naloxone available to individual­s suffering from opioid addiction,” they write, “or those who are at risk of overdose. They do imply that the public health community should acknowledg­e and prepare for the behavioura­l effects we find here.”

Sally Satel echoes Doleac and Mukherjee, both on the moral hazard of naloxone and on whether access to it should continue. Satel, a psychiatri­st who is also a drug- policy scholar at the American Enterprise Institute, says the paper’s findings reinforce what she has heard from patients: “Patients occasional­ly tell me that having naloxone on hand has served as insur- ance against overdose. So, in some instances, it enhances risk taking.”

“That said,” she emphasizes, “we must use it to save people in the immediate term.”

So how can public policy prepare for those “behavi oural effects” f ound by Doleac and Mukher j ee? Satel suggests we look at civil commitment for patients who overdose multiple times in a short period. But she also notes that civil commitment can’t work without good treatment options — and in a lot of places, those aren’t available.

Which brings us back to something that’s easy to forget about the Peltzman Effect: It can be used to argue as much for more regulation as for less. Insurance companies, after all, have been fighting moral hazard for centuries, which is why they reward people who install burglar alarms or fill in their swimming pools ( or, if you like, punish people who don’t do those things). And so, too, can the government — for example, by aggressive­ly ticketing speeders, passing tougher drunk driving laws, or using a combinatio­n of carrots and sticks to help addicts get clean. There are better policy responses to moral hazard than mounting a spike on the steering wheel — or depriving addicts of a second chance at life.

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