National Post (National Edition)

FIVE THINGS ABOUT A BIRTH CONTROL PILL FOR MEN

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1 IT STOPS SPERM FROM SWIMMING

A breakthrou­gh scientific discovery that could be key to developing a male contracept­ive pill changes the way human cells work, switching off the ability of sperm to swim, rendering men temporaril­y infertile.

2 IT USES PEPTIDES

Peptides are short chains of amino acids. They occur naturally but can be created synthetica­lly. The breakthrou­gh came after scientists at England’s Wolverhamp­ton University found some peptides could penetrate sperm cells. Then fertility experts at the University of Aveiro in Portugal, who identified the protein that drives sperm to swim, created a compound that turns the protein off.

3 IT WORKS FAST

Lead researcher professor John Howl of Wolverhamp­ton University said the new compound, made in the lab, showed immediate results. “The results are startling — and almost instant. When you take healthy sperm and add our compound, within a few minutes the sperm basically cannot move,” he said.

4 IT’S ONLY TEMPORARY

The discovery raises the prospect of a fastacting pill or a nasal spray that a man could take hours or even minutes before sex. But researcher­s believe the effects of would wear off in a matter of days.

5 IT COULD CHANGE FAMILY PLANNING

Women are typically advised to stop taking birth-control pills weeks or even months before trying to conceive. Family planning experts said a reversible male contracept­ive could also benefit couples where the woman does not want to take birth-control pills. The compound has been tested in the lab on bovine and human sperm, with live animal tests to start within three years.

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