Ottawa Citizen

DESPITE NUMEROUS LAWSUITS IN THE U.S. AGAINST JOHNSON & JOHNSON, STUDIES ON TALCUM POWDER’S POTENTIAL LINK TO OVARIAN CANCER HAVE YIELDED OFTEN CONTRARY CONCLUSION­S, LEAVING WOMEN TO WONDER: IS IT SAFE TO USE?

EVIDENCE MIXED ON ALLEGED CANCER LINKS

- Sheryl Ubelacker

Baby powder maker Johnson & Johnson has been the subject of a string of lawsuits, including two pending class-action cases in Canada, over allegation­s its product caused ovarian cancer in thousands of women who used it for feminine hygiene.

While some suits already heard in the United States have resulted in juries awarding massive amounts in compensati­on, studies on talcum powder’s potential link to the gynecologi­cal cancer have produced often contrary conclusion­s, leaving some women to wonder: is it safe to use baby powder?

“The evidence that we have is mixed and has to be taken with a little bit of skepticism,” said Dr. James Bentley, a gynecologi­cal oncologist at Dalhousie University in Halifax.

Though some studies have found what appears to be a link, others have found no associatio­n, he said.

There’s also the issue of the way talc molecules interact with the body, which researcher­s don’t have a good handle on, said Bentley.

“This is chronic irritation of the ovary, and we do know that chronic irritation is associated with some carcinomas,” he said. “Do we have really good evidence for that? The literature goes back and forth on this.”

Dr. Daniel Cramer, a professor of obstetrics, gynecology and reproducti­ve biology at Brigham and Women’s Hospital, was the first to sound alarm bells with a 1982 study that drew a link between long-term talc use on the genitals and the developmen­t of ovarian cancer.

Then a 2016 study he led suggested women who routinely sprinkled their vaginal area (known medically as the perineum) with talcum powder had a one-third higher risk of getting ovarian tumours than women who hadn’t been longtime users of the product.

“I’m persuaded by the evidence that talc used in the genital area will reach the ovaries and lymph nodes, and it creates an inflammato­ry environmen­t that could contribute to the developmen­t of cancer,” Cramer said. “I’ve always felt the data was sufficient to warn women about using talc in their feminine hygiene.”

Baby powder is made from talc, a mined mineral that can be naturally contaminat­ed with asbestos, which is known to cause the deadly cancer mesothelio­ma.

The lawsuits brought against Johnson & Johnson have contended the health and cosmetic giant should have put warning labels on the powders.

The most recent judgment against Johnson & Johnson occurred this month, when a St. Louis jury awarded almost US$4.7 billion to 22 women based on claims that decades of using talcum powder for feminine hygiene caused their ovarian cancer.

But the company denies its baby powder, which has been on the market since 1894, causes either mesothelio­ma or ovarian cancer.

“Johnson & Johnson remains confident that its products do not contain asbestos and do not cause ovarian cancer, and intends to pursue all available appellate remedies,” the company said in statement in the wake of the St. Louis case.”

Rhonda Dobson isn’t convinced. She was just 23 when she developed ovarian cancer in 2004 — a disease for which there was no family history — after lifelong use of talcum powder that began with her mother using it on her as a baby.

“That was part of my routine because you have a bath and then you put powder on,” said Dobson, who lives in rural New Brunswick.

While she has been cancer-free since 2009, the 37-year-old said she continues to pay a price for her cancer, which resulted in the removal of her left ovary and fallopian tube, as well as permanent hair loss from chemothera­py. “We trusted them and we believed in their product,” she said.

Mary Krpan, 60, of Hamilton was diagnosed with latestage ovarian cancer in 2014. Despite aggressive treatment, including a complete hysterecto­my and chemothera­py, the disease has now spread to her lungs.

The mother of two daughters started using Johnson & Johnson baby powder after the birth of her eldest child, who is now 31.

Both Dobson and Krpan are part of a yet-to-be-certified national class-action lawsuit, which alleges their cancers were caused by longterm use of talcum powder.

In May, a Quebec court gave the go-ahead for a classactio­n suit filed by the Merchant Law Group, covering women in the province with ovarian cancer who had long used Johnson & Johnson baby powder or Valeant’s Shower to Shower for personal hygiene; Merchant has filed a second class-action in B.C. on behalf of women elsewhere in Canada, which is awaiting certificat­ion.

Despite all the court cases and ongoing debate over the safety of talcum powder, Bentley doesn’t think women who have habitually dusted themselves with the product should panic, especially given the inconsiste­ncy of research results.

“But should you use talc? Probably not,” he said.

WE TRUSTED THEM AND WE BELIEVED IN THEIR PRODUCT.

 ?? PETER POWER / THE CANADIAN PRESS ?? Mary Krpan is going through chemothera­py for ovarian cancer that has spread to her lungs. She is part of a yet-to-be-certified national class-action suit that alleges regular talcum power use can cause cancer.
PETER POWER / THE CANADIAN PRESS Mary Krpan is going through chemothera­py for ovarian cancer that has spread to her lungs. She is part of a yet-to-be-certified national class-action suit that alleges regular talcum power use can cause cancer.

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