Penticton Herald

Causes for shortness of breath

- KEITH ROACH

DEAR DR. ROACH: I am an active 68-year-old woman. I still work part time, walk 2-3 miles a day and enjoy gardening.

In late April, I noticed that I was short of breath after exertion, like when walking upstairs or with intensive gardening. Two weeks later, I was so short of breath that I was hospitaliz­ed. I had a chest CAT scan, an echocardio­gram and a nuclear stress test. The only finding was “a ground glass opacity in my lower lobes.”

I saw a pulmonary doctor and had pulmonary function tests, which were normal. I was treated with Levaquin when hospitaliz­ed, and have been on Symbicort (two puffs twice a day).

My doctor thinks I had viral pneumonia and will have an eight-week recovery. I’m still not feeling well. I tire easily and am short of breath on exertion. Thoughts?

ANSWER: A “ground glass” opacity is a radiology term describing the appearance of the lung tissue on X-ray; it doesn’t mean anything literally about glass. The list of possibilit­ies (doctors call this a “differenti­al diagnosis”) for a bilateral (both lungs) ground glass opacity is very large. There are a lot of lung diseases that may look that way.

Viral pneumonia is one. If that’s the case, the X-ray gradually will return to normal. The uncertaint­y is reflected in your treatment: Levaquin is a powerful antibiotic that treats both common and atypical bacterial pneumonia, whereas Symbicort is a medicine used mostly for asthma and chronic obstructiv­e pulmonary disease.

The fact that your pulmonary function tests were normal is very good news: Lung physiology (that is, how well your lungs work) is more important than how they appear on an X-ray. The symptoms you have are nonspecifi­c and compatible with many lung diseases, including recent infection.

I wholeheart­edly endorse going back to the pulmonary doctor: Some of the possibilit­ies (such as pulmonary fibrosis, sarcoidosi­s and fungal infection) will benefit from treatment. Sometimes a biopsy is necessary to make a diagnosis.

DEAR DR. ROACH: I”m a 62-year-old male. In the six months since I was put on metformin, I have had two diverticul­itis attacks (I’d never had one before). I believe the timing of these attacks is more than circumstan­tial. There have been no other changes in my diet or lifestyle.

Could the metformin be messing with my metabolism in such a way as to cause or exacerbate these attacks”

ANSWER: Although logically it”s impossible to prove that the metformin isn”t causing the diverticul­itis attacks, a review of Food and Drug Administra­tion reports makes me think that while it may be possible, it’s unlikely. In a nine-year period, there were almost 23,000 adverse events reported on metformin (it’s a very commonly used drug). Of those, 50 of them (0.2 per cent) were diverticul­itis.

Diverticul­a are pouches in the colon, thought to be due to higher colon pressure. They are especially common in people with constipati­on. Metformin acts predominan­tly by reducing the amount of sugar produced in the liver, but it can cause diarrhea. I don”t know how metformin would cause diverticul­itis. Diverticul­itis is more prevalent in people in their 50s and 60s, so it’s more likely that this is just chance, in my opinion.

Dr. Roach regrets that he is unable to answer individual letters, but will incorporat­e them in the column whenever possible. Readers may email questions to ToYourGood­Health@med.cornell.edu or request an order form of available health newsletter­s at 628 Virginia Dr., Orlando, FL 32803.

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