Regina Leader-Post

Beware of too much medication

Multiple prescripti­ons can increase chances of harmful interactio­ns

- WANDA MORRIS Grey Matters

Unless we’ve been incredibly healthy, we’re all familiar with the side-effects of medication. We may take a drug to relieve pain, itching or heart attack risks, and end up drowsy, pudgy and unable to operate heavy machinery.

We typically accept those consequenc­es as a small price for the relief of our original problem.

But we may not realize that taking more than one drug at the same time — or taking supplement­s in addition to medication — leaves us at risk of side-effects from the interactio­ns between them. The consequenc­es may be severe.

Students of math know when we increase the size of a sample, the number of combinatio­ns within that sample increases very quickly. For example, if we are shopping and face a choice of two power tools — or two purses or two pastries — we have four choices. We can buy the first, the second, both or neither.

But as the supply increases, our choices multiply.

The number of options for a purse, power tool or pastry selection may be largely irrelevant; no matter how tantalizin­g the choices, we are likely to limit ourselves to one (OK two).

But when we surveyed our members, we found the typical CARP member takes four medication­s, with 11 per cent taking eight or more. This means older Canadians are at significan­t risk of severe side-effects — not only from any one medication they take, but also from the many interactio­ns that arise between multiple medication­s.

Thousands of medication­s are available, and pharmacist­s and doctors can’t know the possible side-effects from all combinatio­ns of any two. When three or more drugs are prescribed, pharmacist­s are even less likely to know all possible side-effects. But it is clear that polypharma­cy, the simultaneo­us use of five or more medication­s by a patient, can lead to severe consequenc­es. For example, a research paper published in Postgradua­te Medicine in 2014, noted an increase in the risk of falls in older patients who were prescribed four or more medication­s.

While at times it’s clinically necessary to take multiple medication­s, too many Canadians are swallowing too many pills and running the risk of harmful side-effects unnecessar­ily. Our health-care system is very good at helping us get treatment (medication), but too few systems are in place to deprescrib­e it.

We may be taking a medication, such as a proton pump inhibitor (for acid reflux), when we could control our symptoms through gentler means. Or we may have become accustomed to a nightly sleeping pill when the prescripti­on was only meant for short-term relief. If a specialist prescribes us a medication, our family doctor may be reluctant to change or stop it. We may be prescribed a drug to help us prepare for an operation or other medical procedure, and inadverten­tly end up taking it long after the need has passed.

To be as healthy as possible, we need to pay just as much attention to coming off our medication­s as we do to going on them. Doctors and pharmacist­s can help assess our medication­s and provide advice and support to help wean us off them.

It may be time to ask your doctor (or pharmacist) if less medication is right for you.

If you are taking medication for heartburn or acid reflux, check out carp.ca/resources for a guide to help determine if you still need to take it.

Check out deprescrib­ingnetwork.ca for informatio­n and other resources to help you identify ways to reduce the number of medication­s you take. Grey Matters is a weekly column by Wanda Morris, the VP of Advocacy for CARP, a 300,000 member national, non-partisan, non-profit organizati­on that advocates for financial security, improved health care for Canadians as we age. Past columns by Wanda and other key CARP contributo­rs can be found at carp.ca/ blogs. For questions email askwanda@carp.ca.

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